Results 41 to 50 of about 9,343 (242)

Structure and conserved function of iso-branched sphingoid bases from the nematode Caenorhabditis elegans [PDF]

, 2017
Sphingolipids are bio-active metabolites that show structural diversity among eukaryotes. They are essential for growth of all eukaryotic cells but when produced in an uncontrolled manner can lead to cell death and pathologies including auto-immune ...
Feng, Suihan, Hannich, J. Thomas, Mellal, Denia, Riezman, Howard, Zumbuehl, Andreas   +4 more
core   +2 more sources

Dose-Dependent Effects on Sphingoid Bases and Cytokines in Chickens Fed Diets Prepared with Fusarium Verticillioides Culture Material Containing Fumonisins

Toxins, 2015
In chickens, the effect of mycotoxins, especially fumonisins (FB), in the gastrointestinal tract (GIT) is not well documented. Thus, this study in broiler chicks determined the effects of consuming diets prepared with Fusarium verticillioides culture ...
Bertrand Grenier, Heidi E. Schwartz-Zimmermann, Sylvia Caha, Wulf Dieter Moll, Gerd Schatzmayr, Todd J. Applegate   +5 more
doaj   +1 more source

Ramadan intermittent fasting is associated with ameliorated inflammatory markers and improved plasma sphingolipids/ceramides in subjects with obesity: lipidomics analysis

Scientific Reports, 2023
Intermittent fasting (IF) is associated with enormous metabolic alterations that underpin its diverse health effects. Changes in lipid metabolism, particularly ceramides, and other sphingolipids, are among the most notable of these alterations.
Mohamed Ibrahim Madkour, Md Torikul Islam, Trevor S. Tippetts, Kamrul H. Chowdhury, Lisa A. Lesniewski, Scott A. Summers, Falak Zeb, Dana N. Abdelrahim, Refat AlKurd, Husam M. Khraiwesh, Katia H. AbuShihab, Asma AlBakri, Khaled Obaideen, MoezAlIslam E. Faris   +13 more
doaj   +1 more source

3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells. [PDF]

, 2016
Although several reports describe the metabolic fate of sphingoid bases and their analogs, as well as their action and that of their phosphates as regulators of sphingolipid metabolizing-enzymes, similar studies for 3-ketosphinganine (KSa), the product ...
Abad, José Luis, Bedia, Carmen, Casas, Josefina, Delgado Cirilo, Antonio, Fabriàs, Gemma, González, Jèssica, Ordoñez, Yadira F.   +6 more
core   +1 more source

Synthesis of ceramides using N-hydroxysuccinimide esters

Journal of Lipid Research, 1972
Fatty acyl esters of N-hYdroxYSuccinimide have been used to directly N-acylate sphingenine or sphinganine, forming the corresponding ceramides. The reaction proceeds in excellent yield (84–96%) from small amounts of starting material (10–20 mg).
David E. Ong, Robert N. Brady
doaj   +1 more source

Updates in Rhea - an expert curated resource of biochemical reactions. [PDF]

, 2016
Rhea (http://www.rhea-db.org) is a comprehensive and non-redundant resource of expert-curated biochemical reactions designed for the functional annotation of enzymes and the description of metabolic networks.
Aimo, L., Axelsen, K.B., Bougueleret, L., Bridge, A., Coudert, E., Hyka-Nouspikel, N., Lombardot, T., Moretti, S., Morgat, A., Niknejad, A., Onwubiko, J., Pagni, M., Pozzato, M., Redaschi, N., Rosanoff, S., Xenarios, I.   +15 more
core   +2 more sources

Preparation of 13C-labeled ceramide by acetic acid bacteria and its incorporation in mice

Journal of Lipid Research, 2010
We prepared 2-hydroxypalmitoyl-sphinganine (dihydroceramide) labeled with a stable isotope by culturing acetic acid bacteria with 13C-labeled acetic acid.
Hiroyuki Fukami, Hideki Tachimoto, Mikiya Kishi, Takayuki Kaga, Hatsue Waki, Machiko Iwamoto, Yasukazu Tanaka   +6 more
doaj   +1 more source

Vitamin K2 as a New Modulator of the Ceramide De Novo Synthesis Pathway

Molecules, 2021
The aim of the study was to evaluate the influence of vitamin K2 (VK2) supplementation on the sphingolipid metabolism pathway in palmitate-induced insulin resistant hepatocytes.
Adrian Kołakowski, Piotr F. Kurzyna, Hubert Żywno, Wiktor Bzdęga, Ewa Harasim-Symbor, Adrian Chabowski, Karolina Konstantynowicz-Nowicka   +6 more
doaj   +1 more source

Metabolic Characterization of the Common Marmoset (Callithrix jacchus) [PDF]

, 2015
High-resolution metabolomics has created opportunity to integrate nutrition and metabolism into genetic studies to improve understanding of the diverse radiation of primate species.
Go, Young-Mi, Jones, Dean P., Liang, Yongliang, Promislow, Daniel E. L., Soltow, Quinlyn A., Uppal, Karan, Wachtman, Lynn M.   +6 more
core   +3 more sources

Characterizations of six ethanolamine sphingophospholipids from Paramecium cells and cilia.

Journal of Lipid Research, 1984
Six ethanolamine sphingophospholipids from axenically cultured Paramecium tetraurelia were isolated from cells and purified ciliary fractions, and were characterized.
E S Kaneshiro, D F Matesic, K Jayasimhulu   +2 more
doaj   +1 more source