Phospholipids and Sphingolipids in Osteoarthritis
BiomoleculesMany studies now emphasize the intricate relationship between lipid metabolism and osteoarthritis (OA), a leading cause of disability. This narrative review examines alterations in the levels of phospholipids (PLs) and sphingolipids (SLs) in synovial fluid (SF), plasma, serum, and articular tissues; discusses their role in joint lubrication ...
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Med Research, EarlyView.Tumor‐derived exosomes influence proliferation, invasion, angiogenesis, metabolic adaptation, and resistance to therapy. They also shape the immune landscape by modulating antigen presentation, suppressing cytotoxic lymphocyte activity, and promoting the expansion of immunosuppressive cell populations. Although frequently associated with immune evasion,
Jiale Li +3 more
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Biosynthesis of Unsaturated Sphingolipid Bases by Microsomal Preparations from Oysters
, 1973 Ray K. Hammond, Charles C. Sweeley
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Hydrolysis of lactosylceramide by human galactosylceramidase and GM1‐β‐galactosidase in a detergent‐free system and its stimulation by sphingolipid activator proteins, sap‐B and sap‐C Activator proteins stimulate lactosylceramide hydrolysis [PDF]
, 1994 Alexandra Zschoche +3 more
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Movement Disorders, EarlyView.Abstract Background Very long chain fatty acids (VLCFAs) are an integral component of myelin and the epidermal water barrier. Variants in genes encoding enzymes responsible for catalyzing the first and rate limiting step in the production of VLCFAs, elongation of VLCFAs (ELOVLs), underlie a novel group of metabolic disorders. Objectives The goal was to
Keit Men Wong +24 more
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Isolation and characterization of sphingolipid from Ochromonas danica
, 1970 Mong Ching Wong Ganfield
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Epithelial sphingolipid sorting is insensitive to reorganization of the Golgi by nocodazole, but is abolished by monensin in MDCK cells and by brefeldin A in Caco-2 cells [PDF]
, 1993 Gerrit van Meer, Wouter van ’t Hof
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Impact of Nutrition on Sphingolipid‐Regulated Physiology: A Review
Molecular Nutrition &Food Research, EarlyView.Sphingolipids (SLs) play a role in multiple, if not all physiological processes. This review summarizes the current knowledge on SLs and their role in (patho‐) physiological processes with special regard to dietary and transgenerational effects. Image was created with BioRender.com.
Jonas Voß +2 more
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Sphingolipids of the Stratum Corneum and Lamellar Granules of Fetal Rat Epidemis
, 1984 Philip W. Wertz +3 more
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Molecular Nutrition &Food Research, EarlyView.Extracellular vesicles from Lactobacillus plantarum improved lipid metabolism in HFD‐fed mice by regulating hepatic genes involved in lipid synthesis and oxidation. They also alleviated intestinal dysfunction by reducing inflammation, enhancing barrier function, and modulating gut microbiota and metabolites, underscoring their therapeutic potential in ...
Shan‐Shan Xu +8 more
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