Results 171 to 180 of about 48,095 (292)

Drosophila models uncover substrate channeling effects on phospholipids and sphingolipids in peroxisomal biogenesis disorders

Michael F. Wangler, Yu-Hsin Chao, Mary R. Roth, Ruth Welti, James A. McNew   +4 more
openalex   +1 more source

The Role of Distinctive Sphingolipids in the Inflammatory and Apoptotic Effects of Electronegative LDL on Monocytes [PDF]

, 2019
Núria Puig, Montserrat Estruch, Lei Jin, José Luís Sánchez-Quesada, Sònia Benı́tez   +4 more
openalex   +1 more source

Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein

The FEBS Journal, EarlyView.
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj, Tadeja Bele, Anastasija Panevska, Gregor Bajc, Jan Kejžar, Miha Bahun, Nataša Poklar Ulrih, Valentina Levak, Matej Skočaj, Larisa Lara Popošek, Peter Veranič, Nataša Resnik, Kristina Sepčić   +12 more
wiley   +1 more source

Conserved sphingolipid metabolism under transcriptomic diversity: a prognostic and therapeutic target in triple-negative breast cancer. [PDF]

J Transl Med
Li J, Chen R, Wang X, Zheng Q, Dai R.
europepmc   +1 more source

Sphingolipids: membrane microdomains in brain development, function and neurological diseases

, 2017
Anne S. Olsen, Nils J. Færgeman
openalex   +1 more source

The antifungal Aureobasidin A and an analogue are active against the protozoan parasiteToxoplasma gondiibut do not inhibit sphingolipid biosynthesis [PDF]

, 2017
Amjed Qays Ibrahim Alqaisi, Alison Mbekeani, M. Bassas Llorens, Åke P. Elhammer, Paul W. Denny   +4 more
openalex   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, EarlyView.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source

The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations. [PDF]

Nat Commun
Chen Y, Zhang P, Huang M, Kachroo P, Checa A, Chen Q, Mendez K, Stav M, Prince N, Begum S, Aparicio A, Guo T, Sharma R, Chu SH, Kelly RS, Hecker J, Akenroye A, Dahlin A, Weiss ST, McGeachie M, Wheelock CE, Lasky-Su JA.   +21 more
europepmc   +1 more source

Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang, Zhiqin Fang, Lam C. Tsoi, Johann E. Gudjonsson   +3 more
wiley   +1 more source

Prosaposin Is Cleaved Into Saposins by Multiple Cathepsins in a Progranulin-Regulated Fashion. [PDF]

J Neurochem
Hodul M, Lane-Donovan C, Cheang ES, Gao V, Sampognaro PJ, Mambou EA, Yang Z, Kao AW.   +7 more
europepmc   +1 more source