Results 11 to 20 of about 851,389 (262)
Sphingolipid signaling in renal fibrosis [PDF]
Matrix Biology, 2018 Over the last decade, various sphingolipid subspecies have gained increasing attention as important signaling molecules that regulate a multitude of physiological and pathophysiological processes including inflammation and tissue remodeling.
Huwiler A, Pfeilschifter J
core +5 more sources
The yeast sphingolipid signaling landscape [PDF]
Chemistry and Physics of Lipids, 2014 Sphingolipids are recognized as signaling mediators in a growing number of pathways, and represent potential targets to address many diseases. The study of sphingolipid signaling in yeast has created a number of breakthroughs in the field, and has the potential to lead future advances.
Yusuf A. Hannun, Nabil Matmati
exaly +5 more sources
Sphingolipid Signaling in Plants
, 2009 Until relatively recently, plant sphingolipids were generally considered to be minor cellular components of limited importance. However, research over the last decade has shown that sphingolipids play key roles in many aspects of plant biology, including reproduction, development and also biotic and abiotic stress.
Michaelson, L. V., Napier, J. A.
openaire +2 more sources
Influenza Viral Manipulation of Sphingolipid Metabolism and Signaling to Modulate Host Defense System [PDF]
Scientifica, 2014 Viruses attempt to create a distinctive cellular environment to favor viral replication and spread. Recent studies uncovered new functions of the sphingolipid signaling/metabolism during pathogenic virus infections.
Madhuvanthi Vijayan, Bumsuk Hahm
doaj +2 more sources
Ethylene modulates sphingolipid synthesis in Arabidopsis [PDF]
Frontiers in Plant Science, 2015 Sphingolipids have essential structural and bioactive functions in membranes and in signaling. However, how plants regulate sphingolipid biosynthesis in the response to stress remains unclear.
Jian-xin eWu +4 more
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Sphingolipid-Based Synergistic Interactions to Enhance Chemosensitivity in Lung Cancer Cells
Cells, 2023 Tumor heterogeneity leads to drug resistance in cancer treatment with the crucial role of sphingolipids in cell fate and stress signaling. We analyzed sphingolipid metabolism and autophagic flux to study chemotherapeutic interactions on the A549 lung ...
Susana Mesén-Porras +6 more
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Deciphering the link between salicylic acid signaling and sphingolipid metabolism [PDF]
Frontiers in Plant Science, 2015 The field of plant sphingolipid biology has evolved in recent years. Sphingolipids are abundant in cell membranes, and genetic analyses revealed essential roles for these lipids in plant growth, development, and responses to abiotic and biotic stress ...
Diana eSánchez-Rangel +5 more
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Sphingolipid metabolism and signaling in cardiovascular diseases
Frontiers in Cardiovascular Medicine, 2022 Sphingolipids are a structural component of the cell membrane, derived from sphingosine, an amino alcohol. Its sphingoid base undergoes various types of enzymatic transformations that lead to the formation of biologically active compounds, which play a ...
Sonia Borodzicz-Jażdżyk +5 more
doaj +3 more sources
DNASphingolipid metabolism has emerged as a regulatory interface between lipid homeostasis, organelle stress, and genome maintenance. Although sphingolipids are essential structural components of cellular membranes, specific metabolites also function as ...
Lauren Kupec +4 more
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TOR Complex 2-Ypk1 Signaling Maintains Sphingolipid Homeostasis by Sensing and Regulating ROS Accumulation [PDF]
Cell Reports, 2014 Reactive oxygen species (ROS) are produced during normal metabolism and can function as signaling molecules. However, ROS at elevated levels can damage cells.
Brad J. Niles +3 more
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