Results 1 to 10 of about 39,549 (288)

Plasma sphingolipids mediate the association between gut microbiome composition and type 2 diabetes risk in the HELIUS cohort: a case-cohort study [PDF]

BMJ Open Diabetes Research & Care
Introduction The association between the gut microbiome and incident type 2 diabetes (T2D) is potentially partly mediated through sphingolipids, however these possible mediating mechanisms have not been investigated.
Femke Rutters, Max Nieuwdorp, Mirthe Muilwijk, Irene van Valkengoed, Bert-Jan van den Born, Henrike Galenkamp, Joline W J Beulens, Martin F Overbeek, Mark Davids   +8 more
doaj   +2 more sources

Role and interaction of bacterial sphingolipids in human health

Frontiers in Microbiology, 2023
Sphingolipids, present in both higher animals and prokaryotes, involving in cell differentiation, pathogenesis and apoptosis in human physiological health.
Xiaoye Bai, Xiaoye Bai, Ru Ya, Xiaoyu Tang, Mingwei Cai   +4 more
doaj   +1 more source

Functions of Sphingolipids in Pathogenesis During Host–Pathogen Interactions

Frontiers in Microbiology, 2021
Sphingolipids are a class of membrane lipids that serve as vital structural and signaling bioactive molecules in organisms ranging from yeast to animals.
Jian Wang, Yi-Li Chen, Yong-Kang Li, Ding-Kang Chen, Jia-Fan He, Nan Yao, Nan Yao   +6 more
doaj   +1 more source

Microalgae—Sustainable Source for Alternative Proteins and Functional Ingredients Promoting Gut and Liver Health

Global Challenges, 2023
Dietary proteins derived from animal sources, although containing well‐balanced profiles of essential amino acids, have considerable environmental and adverse health effects associated with the intake of some animal protein‐based products.
Yahav Eilam, Hamdan Khattib, Noam Pintel, Dorit Avni   +3 more
doaj   +1 more source

Sphingolipids of Asteroidea and Holothuroidea: Structures and Biological Activities

Marine Drugs, 2021
Sphingolipids are complex lipids widespread in nature as structural components of biomembranes. Commonly, the sphingolipids of marine organisms differ from those of terrestrial animals and plants.
Timofey V. Malyarenko, Alla A. Kicha, Valentin A. Stonik, Natalia V. Ivanchina   +3 more
doaj   +1 more source

Role of circulating sphingolipids in lipid metabolism: Why dietary lipids matter

Frontiers in Nutrition, 2023
Sphingolipids are structural components of cell membranes and lipoproteins but also act as signaling molecules in many pathophysiological processes.
Catherine Calzada, Cécile Vors, Armelle Penhoat, David Cheillan, David Cheillan, Marie-Caroline Michalski   +5 more
doaj   +1 more source

Evaluation of plasma sphingolipids as mediators of the relationship between kidney disease and cardiovascular eventsResearch in context

EBioMedicine, 2023
Summary: Background: Sphingolipids are a family of circulating lipids with regulatory and signaling roles that are strongly associated with both eGFR and cardiovascular disease.
Benjamin Lidgard, Nisha Bansal, Leila R. Zelnick, Andrew N. Hoofnagle, Amanda M. Fretts, William T. Longstreth, Jr., Michael G. Shlipak, David S. Siscovick, Jason G. Umans, Rozenn N. Lemaitre   +9 more
doaj   +1 more source

The therapeutic potential of sphingolipids for cardiovascular diseases

Frontiers in Cardiovascular Medicine, 2023
Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide and Inflammation plays a critical role in the development of CVD.
Sapir Ya'ar Bar, Noam Pintel, Hesen Abd Alghne, Hesen Abd Alghne, Hamdan Khattib, Hamdan Khattib, Dorit Avni, Dorit Avni   +7 more
doaj   +1 more source

Sphingolipids in plant immunity

Phytopathology Research, 2022
Sphingolipids (lipids with a sphingoid base backbone) are important components of eukaryotic membrane systems and key signaling molecules that are essential for controlling cellular homeostasis, acclimating to stress, and regulating plant immunity ...
Hong-Yun Zeng, Nan Yao
doaj   +1 more source

Sphingolipid metabolism in brain insulin resistance and neurological diseases

Frontiers in Endocrinology, 2023
Sphingolipids, as members of the large lipid family, are important components of plasma membrane. Sphingolipids participate in biological signal transduction to regulate various important physiological processes such as cell growth, apoptosis, senescence,
Meng Mei, Maochang Liu, Yan Mei, Jing Zhao, Yang Li   +4 more
doaj   +1 more source