Results 11 to 20 of about 45,038 (292)
European Respiratory Review, 2019 Sphingolipids are a distinct class of lipid molecules widely found in nature, principally as cell membrane constituents. After initial uncertainty about their function, sphingolipids have been increasingly recognised to be metabolically active entities ...
Raja Chandra Chakinala +4 more
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Kidney International, 2000 A significant corpus of work over the last decade has firmly established an important role for sphingolipids in a variety of important biological processes. Such processes include signaling events related to cell growth, differentiation, programmed cell death, and stress responses. These processes not only involve those sphingolipids that accumulate as
Alfred Merrill, Eva-Marie Schmelz
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Sphingolipids and Mitochondrial Dynamic
Cells, 2020 For decades, sphingolipids have been related to several biological functions such as immune system regulation, cell survival, and proliferation. Recently, it has been reported that sphingolipids could be biomarkers in cancer and in other human disorders ...
Lais Brigliadori Fugio +2 more
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Sphingolipids in ischemic stroke [PDF]
Атеросклероз, 2022 Determination of new biomarkers involved in the pathogenesis of ischemic stroke is an extremely important task from the point of view of identifying possible mechanisms for preventing the occurrence of an acute event, better diagnosis, and influencing ...
Anastasia A. Rogozhina
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, 2021 Although sphingolipids are ubiquitous components of cellular membranes, their abundance in cells is generally lower than glycerolipids or cholesterol, representing less than 20% of total lipid mass.
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Sphingolipids and atherosclerosis
Atherosclerosis, 2013 The atherosclerotic lesion contains a high amount of sphingolipids, a large group of structurally diverse lipids that regulate distinct biological functions beyond their role as structural membrane components. Assessment of their role in atherogenesis has been enabled after genes that regulate their metabolism had been identified and facilitated by the
Hornemann, Thorsten, Worgall, Tilla S
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Sphingolipids and impaired hypoxic stress responses in Huntington disease. [PDF]
, 2023 Huntington disease (HD) is a debilitating, currently incurable disease. Protein aggregation and metabolic deficits are pathological hallmarks but their link to neurodegeneration and symptoms remains debated.
Niran Maharjan +20 more
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Metabolic variation during development in culture of Leishmania donovani promastigotes [PDF]
, 2011 The genome sequencing of several Leishmania species has provided immense amounts of data and allowed the prediction of the metabolic pathways potentially operating.
Cordeiro-da-Silva, Anabela +8 more
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Topical Collection: New Insights on Sphingolipids in Health and Disease. [PDF]
, 2023 The last two decades have boosted research on sphingolipids as bioactive and signaling molecules [...]
Huwiler, Andrea, Andrea Huwiler
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Sphingolipids in Inflammation [PDF]
Mediators of Inflammation, 2018 The etiology of many diseases results from the dysregulation of inflammation. Understanding the molecular mechanisms controlling the inflammatory response is essential to formulate therapeutic strategies for the treatment of inflammatory conditions. In fact, substantial research has unveiled important aspects of the inflammatory machinery, both at the ...
Elisabetta Albi +2 more
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