Results 31 to 40 of about 46,072 (254)

Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations [PDF]

open access: yes, 2009
Sphingolipids have essential roles as structural components of cell membranes and in cell signalling, and disruption of their metabolism causes several diseases, with diverse neurological, psychiatric, and metabolic consequences.
S. Campbell   +390 more
core   +1 more source

Targeted Sphingolipid Analysis in Heart, Gizzard, and Breast Muscle in Chickens Reveals Possible New Target Organs of Fumonisins

open access: yesToxins, 2022
Alteration of sphingolipid synthesis is a key event in fumonisins toxicity, but only limited data have been reported regarding the effects of fumonisins on the sphingolipidome.
Philippe Guerre   +3 more
doaj   +1 more source

Sphingolipids in Hematopoiesis: Exploring Their Role in Lineage Commitment

open access: yesCells, 2021
Sphingolipids, associated enzymes, and the sphingolipid pathway are implicated in complex, multifaceted roles impacting several cell functions, such as cellular homeostasis, apoptosis, cell differentiation, and more through intrinsic and autocrine ...
Yasharah Raza   +2 more
doaj   +1 more source

Metabolic Labeling of Yeast Sphingolipids with Radioactive D-erythro-[4,5-3H]dihydrosphingosine

open access: yesBio-Protocol, 2013
Yeast sphingolipids can be metabolically labeled with exogenously added radioactive precursors. Here we describe a method to label ceramides and complex sphingolipids of Saccharomyces cerevisiae with a radioactive ceramide precursor, D-erythro-[4, 5-3H ...
Takefumi Karashima   +2 more
doaj   +1 more source

Plant sphingolipids: their importance in cellular organization and adaption [PDF]

open access: yes, 2016
Sphingolipids and their phosphorylated derivatives are ubiquitous bio-active components of cells. They are structural elements in the lipid bilayer and contribute to the dynamic nature of the membrane. They have been implicated in many cellular processes
Michaelson, L. V.   +6 more
core   +1 more source

Circulating Sphingolipids and Glucose Homeostasis: An Update

open access: yes, 2023
International audienceSphingolipids are a family of lipid molecules produced through different pathways in mammals. Sphingolipids are structural components of membranes, but in response to obesity, they are implicated in the regulation of various ...
Gyulkhandanyan, Anna   +11 more
core   +1 more source

A Brief Review of FT-IR Spectroscopy Studies of Sphingolipids in Human Cells

open access: yesBiophysica, 2023
In recent years, sphingolipids have attracted significant attention due to their pivotal role in cellular functions and physiological diseases.
Bahar Faramarzi   +4 more
doaj   +1 more source

Thematic Review Series: Sphingolipids. Nuclear sphingolipids: metabolism and signaling*

open access: yesJournal of Lipid Research, 2008
Sphingolipids are most prominently expressed in the plasma membrane, but recent studies have pointed to important signaling and regulatory roles in the nucleus.
Robert W. Ledeen, Gusheng Wu
doaj   +1 more source

Exploring Sphingolipid Implications in Neurodegeneration

open access: yesFrontiers in Neurology, 2020
Over the past decade, it was found that relatively simple sphingolipids, such as ceramide, sphingosine, sphingosine-1-phosphate, and glucosylceramide play important roles in neuronal functions by regulating rates of neuronal growth and differentiation ...
Alice V. Alessenko, Elisabetta Albi
doaj   +1 more source

Dietary Fat and Protein Intake in Relation to Plasma Sphingolipids as Determined by a Large-Scale Lipidomic Analysis

open access: yesMetabolites, 2021
Sphingolipid concentrations have been associated with risk of type 2 diabetes and cardiovascular diseases. Because sphingolipids can be synthesized de novo from saturated fatty acids (SFA), dietary fatty acids may affect plasma sphingolipid ...
Jowy Yi Hoong Seah   +7 more
doaj   +1 more source

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