The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie +5 more
wiley +1 more source
Editorial: The role of glycolipids and sphingolipids in the differentiation and function of innate immune cells. [PDF]
Iwabuchi K, Tsuji M, Kasahara K.
europepmc +1 more source
Enhancing Lipidomics With High‐Resolution Ion Mobility‐Mass Spectrometry
ABSTRACT Lipids, indispensable yet structurally intricate biomolecules, serve as critical regulators of cellular function and disease progression. Conventional lipidomics, constrained by limited resolution for isomeric and low‐abundance species, has been transformed by ion mobility‐mass spectrometry (IM‐MS).
Gaoyuan Lu +3 more
wiley +1 more source
Proteomic and Lipidomic Profiling of Immune Cell‐Derived Subpopulations of Extracellular Vesicles
ABSTRACT Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study aimed to determine proteomic and lipidomic differences among four EV subpopulations. Large and small EVs
Anna Lischnig +6 more
wiley +1 more source
Dysregulated metabolism of ceramides and glycosphingolipids in Parkinson's disease. [PDF]
Peng YF, Chen SJ, Li JL, Lin CH, Kuo CH.
europepmc +1 more source
Novel Wide‐Spectrum Virucidal Lipid Nanoparticles
POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins +10 more
wiley +1 more source
Sphingolipids in Gaucher disease: a systematic review. [PDF]
Lake A, Fuller M.
europepmc +1 more source
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations. [PDF]
Chen Y +21 more
europepmc +1 more source

