Results 161 to 170 of about 41,788 (297)

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

Ceramide in Type 2 Diabetes and Obesity: Modulation by Nutrients and Dietary Patterns and Opportunities to Prevent and/or Manage Metabolic-Related Conditions. [PDF]

Metabolites
Gaggini M, Suman AF, Vassalle C.
europepmc   +1 more source

Sphingolipids in Apoptosis

, 2012
Forty years ago, the term “apoptosis” was introduced to describe a form of programmed cell death. Key players that mediate apoptosis at the molecular level such as caspases, death receptors, Bcl-2 family members have since been identified and their ...
Voelkel-Johnson, C., Tirodkar, T.S.
core  

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco, David Uroz‐Torres, Ana Soriano‐Lerma, Miguel Soriano, Jose Antonio García‐Salcedo, Maria Teresa Arias‐Moliz   +5 more
wiley   +1 more source

Sphingolipid homeostasis and dysregulation in liver function and disease. [PDF]

Life Metab
Lan J, Pan Z, Dong W, Wang J, Zhang C, Zhang Y, Wu Y, Jin J.   +7 more
europepmc   +1 more source

Temperature, but not acidification, influences the growth and lipid profile of juvenile sand whiting, Sillago ciliata (Cuvier 1829)

Journal of Fish Biology, EarlyView.
Abstract Seafood provides an essential source of macro‐ and micronutrients for coastal communities worldwide. Climate change is a key threat to seafood security, altering the sizes, abundances, distributions, physiology and ecological interactions of fisheries species, and increasingly, there is evidence of impacts to seafood nutritional quality.
Tanika C. Shalders, Melissa Tan, Karina C. Hall, Melinda A. Coleman, Brendan Kelaher, Curtis Champion, Kirsten Benkendorff   +6 more
wiley   +1 more source

Behind the membranous curtain-lipid dynamics and functions in coronaviral replication. [PDF]

J Virol
Salisch F, Müller-Ruttloff C.
europepmc   +1 more source

Pangenome analysis reveals the genetic mechanism underlying high‐altitude adaptation in Qinghai–Xizang (Tibet) Plateau Rhododendron

Journal of Integrative Plant Biology, EarlyView.
Pan‐genome analysis reveals that high‐altitude Rhododendron species resist alpine cold stress by rapidly sensing and engaging the chilling response pathway and genes that directly and indirectly protect the plant from UV radiation. Heritable genomic features such as long terminal repeats contribute to the adaptive diversification of Rhododendron ...
Haoyang Zhou, Zhongping Xu, Fanhuang Zeng, Haiyu Sang, Zhenhua Liu, Miao Sun, Qiang Fu, Kaige Zhao, Daming Tan, Manzhu Bao, Shuangxia Jin, Xiuqun Liu   +11 more
wiley   +1 more source

Very long chain sphingolipids govern brain myelination by regulating oligodendrocyte differentiation and membrane microdomain integrity. [PDF]

J Transl Med
Sun H, Mo L, Cao M, Tian Y, Mo L, Ni Z, Zhang S, Huang X, Wang Y, Lam SM, Shui G.   +10 more
europepmc   +1 more source

The algal homolog of the plant CER1 and CER3 proteins is a bifunctional hydrocarbon‐forming enzyme

New Phytologist, EarlyView.
Schematic representation of the proposed reactions carried out by a CER1/3 protein from green algae. CoA, coenzyme A; CTD, C‐terminal domain; Cys, catalytic cysteine of C‐terminal domain; His, catalytic histidines of N‐terminal domain; NTD, N‐terminal domain.
Ángel Baca‐Porcel, Bertrand Légeret, Alexandre Six, Mallaury Cabanel, Mathilde Le Cossec, Arthur Guegano, Damien Sorigué, Yonghua Li‐Beisson, Florian Veillet, Fred Beisson   +9 more
wiley   +1 more source