Results 171 to 180 of about 46,072 (254)

Mitochondrial permeability transition in skeletal muscle phenocopies muscle alterations seen in cancer cachexia and other wasting conditions

The Journal of Physiology, EarlyView.
Abstract figure legend Skeletal muscle wasting conditions are characterized by muscle fibre atrophy, mitochondrial respiratory dysfunction, mitochondrial depletion and fragmentation of acetylcholine receptor (AChR) cluster at the neuromuscular junction.
Maya Semel, Cole Lukasiewicz, Sarah Skinner, Mark R. Viggars, Sung Gi Noh, Martin Picard, Abbey‐Gale Mannings, Michael S. Cohen, Dennis W. Wolan, Terence E. Ryan, Russell T. Hepple   +10 more
wiley   +1 more source

<i>Porphyromonas gingivalis</i>-Derived Phosphoglycerol-isoC17:0-Dihydroceramide Reprograms Sphingolipid Metabolism in Human OECM-1 Oral Squamous Cell Carcinoma Cells. [PDF]

FASEB Bioadv
Yamada C, Ho A, Sanz N, Peng G, Xu R, Mao C, Yuan X, Momen-Heravi F, Edwards PC, Nichols F, Movila A.   +10 more
europepmc   +1 more source

Biofilm Development and Stage‐Specific Multi‐Omics Analysis of Metschnikowia bicuspidata Associated With Milky Disease in the Eriocheir sinensis

Aquaculture, Fish and Fisheries, Volume 6, Issue 6, December 2026.
ABSTRACT Metschnikowia bicuspidata, the causative agent of milky disease in the Chinese mitten crab (Eriocheir sinensis), is an important aquatic pathogenic yeast in freshwater aquaculture. However, the developmental characteristics and molecular regulation of its biofilm formation remain poorly understood.
Yitong Deng, Yue Wang, Zheyi Lei, Junchi Xu, Jie Bao, Hongbo Jiang   +5 more
wiley   +1 more source

Cucumber Mosaic Virus Promotes Sphingolipid Biosynthesis to Alleviate Host Unfolded Protein Response (UPR)-Mediated Immunity. [PDF]

Mol Plant Pathol
Yao J, Wu S, Gao S, Xiang Z, Wang Q, Ye F, Liao Q, Gu Z, Du Z.   +8 more
europepmc   +1 more source

Circulating Plasma Adiposomes as a Partial Lipidomic Readout of Matched Subcutaneous Adipose Tissue: Implications for Interorgan Communication

Comprehensive Physiology, Volume 16, Issue 6, December 2026.
In 22 participants, circulating plasma adiposome lipidomes showed moderate global concordance with matched subcutaneous adipose tissue adiposomes across 773 lipid features and 18 classes. These findings support plasma adiposomes as accessible, non‐invasive biomarkers of adipose lipid biology while recognizing compartment‐specific differences.
Mohamed Saad Rakab, Imaduddin Mirza, Elsayed Metwally, Mohammed Morsy, Carlos Martinez, Mario Masrur, Chandra Hassan, Francesco M. Bianco, Brian T. Layden, Abeer M. Mahmoud   +9 more
wiley   +1 more source

Sphingolipids and Mortality in Hemodialysis: Innocent Bystanders or Causal Culprits? [PDF]

J Am Soc Nephrol
Saum KL, Pennathur S.
europepmc   +1 more source

Lipid membrane composition modulates the structural evolution of early‐stage human islet amyloid polypeptide amyloids

Protein Science, Volume 35, Issue 12, December 2026.
Abstract Progressive β cell death resulting from the aggregation of human islet amyloid polypeptide (hIAPP) in the pancreas is a molecular driver of type 2 diabetes (T2D). Recent studies from our group have shown that hIAPP forms two distinct amyloid oligomers: on‐path donut oligomers (DOs) and off‐path round oligomers (ROs). Previous studies have also
Daniel Warren, Jadon Sitton, Joshua Skrehot, Dmitry Kurouski   +3 more
wiley   +1 more source

Protocol for high-throughput, automated, solid-phase extraction of sphingolipids from human urine. [PDF]

STAR Protoc
Nicholson RJ, Maschek JA, Lonergan T, Summers SA.   +3 more
europepmc   +1 more source

Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10931-10949, December 2026.
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou, Christoforos K. Travlos, Lucas Lage Marinho, Thomas A. Mavrakanas, João Pedro Ferreira, Abhinav Sharma   +5 more
wiley   +1 more source

Proteomic Analysis of Sphingolipid Metabolic Enzymes with Risk of Bladder Cancer Incidence and Mortality in the Atherosclerosis Risk in Communities Study. [PDF]

Cancer Prev Res (Phila)
Marrone MT, Bagley E, Butler KR, Couper DJ, Joshu CE, Platz EA, Ogretmen B.   +6 more
europepmc   +1 more source