Results 191 to 200 of about 46,072 (254)

Alpinia oxyphylla Miq.: Chemical Constituents, Neuroprotective and Metabolic Effects, and Translational Challenges—A Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 11, November 2026.
Alpinia oxyphylla Miq. (AOM), a medicinal and edible resource, contains diphenylheptanoids, polysaccharides, flavonoids, terpenoids, and phenolic acids. These constituents exert multi‐target synergistic effects by modulating neuroinflammation, oxidative stress, and the PI3K/Akt pathway, thereby improving Alzheimer's disease, Parkinson's disease, and ...
Ziyan Yang, Hemei Yuan, Dengyou Nie, Jun Sheng, Titi Liu, Huanhuan Xu   +5 more
wiley   +1 more source

The role of sphingolipids in major depressive disorder and associated cognitive impairment: interactions with monoaminergic signaling, neuroinflammation, and neurogenesis. [PDF]

Mol Psychiatry
Hoertel N, Mühle C, Müller CP, Chaieb H, Scheer V, Fayad M, Sánchez-Rico M, Limosin F, Kornhuber J.   +8 more
europepmc   +1 more source

Extracellular Vesicles for Space Biomedical Research

Journal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
Microgravity reshapes EV biogenesis and cargo selection, which brings new opportunities for longitudinal liquid‐biopsy readouts of stress and aging‐like trajectories, as well as the regenerative products in spaceflight research. ABSTRACT Extracellular vesicles (EVs) are regulated, information‐rich nanovesicles that reflect aspects of parent‐cell state,
Samantha Ali, Brian I. Molina Diaz, Pei Zhuang, Zachary Greenberg, Ye Zhang, Jeffrey Richards, Danny Carlos, Stefanie Countryman, Christiaan Leeuwenburgh, Luke P. Lee, Mei He   +10 more
wiley   +1 more source

Measles virus reprograms CD4⁺ T-cell sphingolipid and fatty acid metabolism to facilitate infection. [PDF]

Front Cell Dev Biol
Grijalva Yépez MF, Cordes YL, Fekete A, Schumacher F, Kleuser B, Avota E.   +5 more
europepmc   +1 more source

Multiple Lipid Scramblases Regulate the Quantity of Extracellular Vesicle Production From the Plasma Membrane

Journal of Extracellular Biology, Volume 5, Issue 11, November 2026.
Cells are wrapped in a double‐sided plasma membrane made up of fatty lipids that can release lipid‐wrapped fragments called extracellular vesicles (EVs). Diverse scramblase proteins, which shuffle lipids across cellular membranes in both directions, can promote EV release.
Bianca L. Guerra, Tanner Chase White, Alissa Rumin, Lauren Pitts, Alexander Nguyen, Vanshika Chauhan, Dinah Loerke, Ann M. Wehman   +7 more
wiley   +1 more source

Sphingolipids in Inflammation

Mediators of Inflammation, 2018
Elisabetta Albi, Alice Alessenko, Sabine Grösch   +2 more
doaj   +1 more source

Eigenlipids for exploring lipid biology. [PDF]

J Lipid Res
Sing N, Smith AAT, Dakic A, Yi C, Salim A, Giles C, Meikle PJ.   +6 more
europepmc   +1 more source

Matrix Vesicle‐Associated SMS2 as a Novel Mediator of Biomineralization

Journal of Extracellular Biology, Volume 5, Issue 11, November 2026.
ABSTRACT SGMS2, a gene encoding plasma membrane‐resident sphingomyelin synthase 2, SMS2, has emerged as an important determinant of skeletal ossification. Heterozygous SGMS2 variants are associated with a broad spectrum of bone phenotypes, ranging from rickets‐like deformities in childhood to early‐onset osteoporosis, implicating SMS2 in mineralization
Phillip T. Newton, Mathieu Y. Brunet, Jose G. Marchan‐Alvarez, Outi Mäkitie, Joost C. M. Holthuis   +4 more
wiley   +1 more source

The Liver as the Central Regulator of Cholesterol Homeostasis: Statins, Gut Microbiota, Hepatic Inflammation, and the Proposed Oral-Gut-Liver-Artery Axis in Atherogenesis. [PDF]

Metabolites
Cannon M, Peldyak J, Campbell E.
europepmc   +1 more source