Results 191 to 200 of about 61,185 (300)

Flaxseed feeding enriches plasmalogens and glycosphingolipids and alters the esterification site of PUFAs in egg yolk phospholipids based on lipidomics analysis. [PDF]

Food Chem X
Wang Y, Cheng L, Zhang M, Ma Y, Dong L, Li Y, Fang B.   +6 more
europepmc   +1 more source

Sphingosine‐1‐Phosphate Promotes FOS Activation in Osteosarcoma Under Tumor Acidosis

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The tumor microenvironment in solid tumors is characterized by extracellular acidosis, which promotes cancer aggressiveness. In osteosarcoma, the most common primary bone cancer, a highly acidic tumor microenvironment is associated with metastasis and poor prognosis, partly due to metabolic rewiring, including changes in lipid pathways ...
Nicolò Bozzini, Margherita Cortini, Alberto Righi, Agamemnon E. Grigoriadis, Michael Dack, Elizabeta Ilieva, Federica Torricelli, Veronica Manicardi, Nicola Baldini, Sofia Avnet   +9 more
wiley   +1 more source

Altered sphingolipid profile in primary biliary cholangitis: associations with fibrosis and inflammation. [PDF]

Sci Rep
Rogalska M, Błachnio-Zabielska A, Zabielski P, Janica J, Roszczyc-Owsiejczuk K, Pogodzińska K, Andrzejuk A, Dąbrowski A, Flisiak R, Rogalski P.   +9 more
europepmc   +1 more source

High cholesterol absorption efficiency enhances proatherogenic properties of low‐density lipoprotein particles

Journal of Internal Medicine, Volume 299, Issue 6, Page 711-725, June 2026.
Abstract Background and Aims High cholesterol absorption efficiency is determined by genetic variation in small intestinal sterol transporters and affects one‐third of individuals. Their risk for atherosclerotic cardiovascular disease (ASCVD) is increased compared with low cholesterol absorbers, despite similar serum lipid concentrations.
Katariina Öörni, Lauri Äikäs, Maija Ruuth, Feven Tigistu‐Sahle, Reijo Käkelä, Ingmar Wester, Helena Gylling, Piia Simonen   +7 more
wiley   +1 more source

Regulation of Plasmodesmata Function Through Lipid-Mediated PDLP7 or PDLP5 Strategies in <i>Arabidopsis</i> Leaf Cells. [PDF]

Plants (Basel)
Chen X, Liu NJ, Hu JR, Shi H, Gao J, Zhu YX.   +5 more
europepmc   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 350-359, June 2026.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

The ratio of circulatory levels of sphingolipids to steroids predicts asthma exacerbations. [PDF]

Nat Commun
Chen Y, Zhang P, Huang M, Kachroo P, Checa A, Chen Q, Mendez K, Stav M, Prince N, Begum S, Aparicio A, Guo T, Sharma R, Chu SH, Kelly RS, Hecker J, Akenroye A, Dahlin A, Weiss ST, McGeachie M, Wheelock CE, Lasky-Su JA.   +21 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, Volume 16, Issue 5, Page 857-869, May 2026.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

The Involvement of Ceramide, Sphingosine-1-Phosphate and Ganglioside GM1 in Regulating Some Nervous System Functions. [PDF]

Int J Mol Sci
Giussani P, Mauri L, Sonnino S.
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, Volume 16, Issue 5, Page 837-856, May 2026.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source