Results 211 to 220 of about 45,038 (292)

Behind the membranous curtain-lipid dynamics and functions in coronaviral replication. [PDF]

J Virol
Salisch F, Müller-Ruttloff C.
europepmc   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, Volume 13, Issue 52, 18 September 2026.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Rewriting Inflammation in IBD: Lipidomics from Pathogenesis to Clinical Application. [PDF]

Microorganisms
Patteril C, Pezzella C, Puca P, Di Vincenzo F, Lopetuso LR, Laterza L, Napolitano D, Cammarota G, Papa A, Gasbarrini A, Scaldaferri F.   +10 more
europepmc   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, Volume 13, Issue 53, 24 September 2026.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Association of Sphingolipids with All-Cause and Cardiovascular Death in Patients with Kidney Failure Treated with Maintenance Hemodialysis. [PDF]

J Am Soc Nephrol
Lidgard B, Hoofnagle AN, Zelnick LR, de Boer IH, Jensen P, Fretts AM, Siscovick DS, Siscovick DS, Umans JG, Bansal N, Lemaitre RN.   +10 more
europepmc   +1 more source

ENT1 inhibition links oligodendrocyte lipid metabolism to connectivity in tauopathy

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Metabolic dysfunction, altered adenosine signaling, and white matter abnormalities are implicated in tauopathies, but their relationship to network disconnection remains unclear. Myelinating oligodendrocytes may represent a metabolically vulnerable hub linking these processes to circuit dysfunction.
Ching‐Pang Chang, Ching‐Wen Chang, Ching‐Wen Wu, Jian Jing Siew, David Blum, Lee‐Way Jin, You‐Yin Chen, Yijuang Chern   +7 more
wiley   +1 more source

The Sphingolipid Balance and Endothelial Dysfunction in Lysosomal Storage Diseases: Shared Mechanisms in Gaucher, Niemann-Pick and Fabry Disease. [PDF]

Int J Mol Sci
Nekrasova A, Kutsev S, Shestopalov A.
europepmc   +1 more source

Perinatal lead (Pb) exposure and alterations to amyloid beta and metabolic profiles in the brain

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Developmental neurotoxicant exposures (e.g., lead [Pb]) are suspected contributors to dementia. Dementia is characterized by amyloid beta (Aβ) plaques and dysregulated metabolism. To better understand the relationship between environment and dementia risk, we assessed the impact of perinatal Pb exposure on dementia‐related ...
Rachel K. Morgan, Evelyn K. Matei, Junru Pan, Tomoko Ishikawa, Katelyn M. Polemi, Ingrid Bergin, Sean P. Ferris, Hao Wang, Dana C. Dolinoy, Kelly M. Bakulski, Justin A. Colacino   +10 more
wiley   +1 more source

Roles of Ceramide Glucosyltransferase in Controlling Cerebral Microvascular Endothelial Integrity and Angiogenesis Post-Ischemia/Reperfusion. [PDF]

Transl Stroke Res
Mohamud Yusuf A, Zafar M, Hagemann N, Brockmeier U, Schumacher F, Kleuser B, Tertel T, Giebel B, Gulbins E, Hermann DM.   +9 more
europepmc   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1850-1862, September 2026.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source