Results 211 to 220 of about 61,185 (300)

Sarcosine is uniquely modulated by aging and dietary restriction in rodents and humans [PDF]

, 2018
et al,, Fontana, Luigi, Tosti, Valeria
core   +1 more source

Dual Biological Potential: Anticancer and Antibacterial Activities of Bis-α, ω-Bifunctional Sphingolipids from the Marine Sponge Oceanapia ramsayi. [PDF]

ChemMedChem
Keneni DA, Njanje I, Kalinski JJ, Isaacs M, Swart T, Davison C, de la Mare JA, Dorrington RA.   +7 more
europepmc   +1 more source

SYK Signalling in NLRP3 Inflammasome‐Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG

European Journal of Immunology, Volume 56, Issue 5, May 2026.
IC‐mediated inflammatory response—the NLRP3 inflammasome activation, cytokine secretion, and antigen presentation depend on SYK signalling pathways in primary murine microglia. ABSTRACT Viral infections might trigger systemic inflammatory responses characterised by inflammasome activation and cytokine release, driven by immune complex (IC) formation ...
Kristina Mašalaitė, Milda Norkienė, Aurelija Žvirblienė, Asta Lučiūnaitė   +3 more
wiley   +1 more source

Natural Products as the Modulators of Gut Microbiota: A Pool for the Development of New Treatment Against Obesity?

Food Frontiers, Volume 7, Issue 3, May 2026.
Natural compounds regulate gut microbiota by improving microbial balance and increasing probiotics, which boost short‐chain fatty acid production to alleviate insulin resistance and inflammation. Additionally, they stimulate appetite‐suppressing hormones through bile acid signaling, while inhibiting pathogenic bacteria to repair intestinal barrier ...
Hongchao Yuan, Yau‐Yuen Chan, Guang Chen, Lin Xu, Cheng Zhang, Guoyi Tang, Yibin Feng, Ning Wang   +7 more
wiley   +1 more source

PSORI-CM02 Restores Epidermal Differentiation in Psoriasis via the Gut Microbiota-Sphingolipid Axis. [PDF]

Drug Des Devel Ther
Wu Y, Pan S, Yin C, Kong Y, Huo W, Wang Q, Wu J, Li L, Wei J, Lu C, Han L, Lu Y.   +11 more
europepmc   +1 more source

Astragaloside IV Reprograms Spatial Glycolytic Metabolism in Diabetic Kidney: A Microenvironment‐Targeted Immunometabolic Therapeutic Strategy

Food Frontiers, Volume 7, Issue 3, May 2026.
Diabetic nephropathy (DN) is driven by spatially organized immunometabolic dysfunction. Integrating high‐resolution spatial transcriptomics (10× Visium HD) and metabolomics (MALDI‐MSI), we mapped a pathogenic glycolytic blockade within diabetic kidney microenvironments.
Shi Qiu, Zhibo Wang, Sifan Guo, Dandan Xie, Ying Cai, Xian Wang, Yan Wang, Xiaodan Yu, Jinxuan Chai, Hong Yao, Chunsheng Lin, Qiang Yang, Yu Guan, Qiqi Zhao, Songqi Tang, Wenjie Sun, Yiqiang Xie, Aihua Zhang   +17 more
wiley   +1 more source

Innovations in Herbal Functional Beverages: From Green Formulation and Bioactivity Preservation to Sensory Optimization and Regulatory Safety

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Herbal‐extract‐enriched beverages are emerging as promising functional foods that combine sensory appeal with health‐promoting bioactives. This review summarizes their formulation in hot and cold beverages, focusing on processing challenges, physicochemical stability, sensory quality, encapsulation strategies, health benefits, safety, and regulatory ...
Farhang Hameed Awlqadr, Syamand Ahmed Qadir, Ammar B. Altemimi, Rawaa H. Tlay, Mohammed N. Saeed, Othman Abdulrahman Mohammed, Tarek Gamal Abedelmaksoud   +6 more
wiley   +1 more source

Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain Development. [PDF]

J Neurochem
Chinnappa K, Ballorin F, Francis F.
europepmc   +1 more source

Complicated Spastic Paraparesis: Study of a Patient With a De Novo Pathogenic Variant in ELOVL1

International Journal of Developmental Neuroscience, Volume 86, Issue 3, May 2026.
A de novo ELOVL1 variant causes syndromic spastic paraparesis with congenital ichthyosis, cerebellar signs and white matter abnormalities. Long‐term clinical and MRI follow‐up showed mild motor and neuroradiological progression with preserved intelligence and subtle cognitive efficiency decline, supporting the hypothesis of a primary neuronal disease ...
Ylenia Vaia, Eleonora Mura, Fabio Bruschi, Stefania Zambrano, Michela Brena, Gianluca Tadini, Filippo Arrigoni, Clara E. Antonello, Carla Uggetti, Cecilia Parazzini, Pierangelo Veggiotti, Davide Tonduti   +11 more
wiley   +1 more source

Altered Sphingolipids, Glycerophospholipids, and Lysophospholipids Reflect Disease Status in Idiopathic Steroid-Sensitive Nephrotic Syndrome in Children: A Non-Targeted Metabolomic Study. [PDF]

Cells
Kanai T, Ogiso H, Aoyagi J, Kurosaki M, Maru T, Ishii M, Tanimoto K, Yoshino M, Yamashita Y, Tajima T, Nagai R, Aizawa K.   +11 more
europepmc   +1 more source