Results 221 to 230 of about 45,038 (292)

Detergents without a drain: the evolutionary logic (and liability) of sphingolipids. [PDF]

J Lipid Res
Summers SA.
europepmc   +1 more source

Metabolic Reprogramming of Cancer Stem Cells: Targeting Lipid Flux and Mitochondrial Plasticity to Overcome Therapeutic Resistance

Cancer Medicine, Volume 15, Issue 9, September 2026.
Metabolic reprogramming in cancer stem cells: lipid flux, mitochondrial plasticity, and therapeutic resistance. Lipid metabolism in CSCs: de novo lipogenesis, CD36 uptake, FAO, lipid droplets, and membrane remodeling. Mitochondrial dynamics in CSC survival: fusion, fission, mitophagy, OXPHOS switching, and ROS regulation.
Daniel Ejim Uti, Esther Ugo Alum, Josephine E. Egbung, Zuhair M. Mohammedsaleh, Manpreet Kaur, Kranti Kiran Reddy Ealla   +5 more
wiley   +1 more source

Eriosema glomeratum Possessed Interesting Bioactive Constituents and Semisynthetic Derivatives With Relevant Biosynthetic Correlation and Important Chemophenetic Significance

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
A medicinal plant Eriosema glomeratum has potentially lead compounds, erioschalcones A and B, and their semisynthetic derivatives for drug discovery. ABSTRACT Plants are sources of compounds with benefits in human health and animal well‐being. Plant‐based foods may contain huge numbers of different phytochemicals.
Gaétan Tchangou Tabakam, Maurice Ducret Awouafack   +1 more
wiley   +1 more source

1-Deoxysphingolipids require very-long-chain ceramide synthesis to induce ER stress and cytotoxicity. [PDF]

J Biol Chem
Byrnes C, Clarke BA, Zhu H, Lee YT, Majumder S, Kono M, Proia RL.   +6 more
europepmc   +1 more source

Cinerascensosides A and B, Two New Cytotoxic Sulfated Saponins From the Sea Cucumber Holothuria cinerascens

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Two new saponins cinerascensosides A and B (1 and 2) are isolated from the sea cucumber H. cinerascens. Their structures and absolute configurations are established through extensive spectroscopic analysis, DP4+ probability calculation, and ECD calculations.
Tran Thi Hong Hanh, Ninh Thi Ngoc, Le Thi Vien, Nguyen Xuan Cuong, Dao Viet Ha, Nguyen Hoai Nam   +5 more
wiley   +1 more source

Preoperative Cer(d18:1/24:0) Shows Promise as a Candidate Predictor of Plasma Lipid Phenotypes Following Roux-en-Y Gastric Bypass in Women: An Exploratory Analysis of the SURMetaGIT Study. [PDF]

J Obes
Lemos GO, Torrinhas RSM, Pino JMV, Calder PC, Heymsfield SB, Machado NM, Waitzberg DL.   +6 more
europepmc   +1 more source

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease of unknown cause, marked by excessive deposition of extracellular matrix (ECM) components such as collagen. This pathological accumulation results in progressive destruction of the lung architecture and ultimately leads to respiratory failure.
Yining Zhang, Ling Teng, Limin Gong, Yuandong Fu, Minyi Qian   +4 more
wiley   +1 more source

Dysregulation of sphingolipid-metabolizing enzymes in Friedreich's ataxia: <i>In vitro</i> and <i>in vivo</i> insights into therapeutic targeting. [PDF]

iScience
Ramchunder Z, Kalef-Ezra E, Suleman S, Edzeamey FJ, Szunyogh S, Gittins O, Castro Mena N, Wade-Martins R, Valle A, Pourzand C, Anjomani Virmouni S.   +10 more
europepmc   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, Volume 12, Issue 3, Page 219-230, September 2026.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

The role of lipids in neuromodulation for psychiatric disorders: A narrative review. [PDF]

Transl Psychiatry
Karaszewska DM, van Kesteren M, Bergfeld I, Lok A, Assies J, Dols A, van den Munckhof P, Schuurman R, Denys D, Mocking RJT.   +9 more
europepmc   +1 more source