Unlocking the therapeutic potential of sphingolipids in wound healing: from molecular mechanisms to clinical applications. [PDF]
Sujie X +12 more
europepmc +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
Multi-omics reveal phosphatidic acid phosphatases modify Niemann-Pick type C disease severity. [PDF]
Munkacsi AB +19 more
europepmc +1 more source
Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou +10 more
wiley +1 more source
Proteograph™-based proteome and sphingolipidome analyses identified novel serum biomarkers to monitor astronauts' health in spaceflight. [PDF]
Moriggi M +9 more
europepmc +1 more source
Dual Biological Potential: Anticancer and Antibacterial Activities of Bis-α, ω-Bifunctional Sphingolipids from the Marine Sponge Oceanapia ramsayi. [PDF]
Keneni DA +7 more
europepmc +1 more source
Recognizing Early Career Translational Investigators. [PDF]
Nahrendorf M.
europepmc +1 more source
Sphingolipid Expression During Corneal Wound Healing in a Sphingosine Kinase 1 Knockout Model. [PDF]
Basu SK +10 more
europepmc +1 more source
PSORI-CM02 Restores Epidermal Differentiation in Psoriasis via the Gut Microbiota-Sphingolipid Axis. [PDF]
Wu Y +11 more
europepmc +1 more source

