Results 251 to 260 of about 41,788 (297)
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Pharmacological Research, 2003
The sphingolipid field has made significant strides over the past 10 years: from identifying metabolites of the sphingomyelin pathway as second messengers to discerning the molecular biology and biophysics of these lipid-derived second messengers. Building upon this vast basic science literature, scientists from multiple disciplines have begun to ...
Mark, Kester, Richard, Kolesnick
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The sphingolipid field has made significant strides over the past 10 years: from identifying metabolites of the sphingomyelin pathway as second messengers to discerning the molecular biology and biophysics of these lipid-derived second messengers. Building upon this vast basic science literature, scientists from multiple disciplines have begun to ...
Mark, Kester, Richard, Kolesnick
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2022
Sphingolipids and cholesterol are two lipid partners on cellular membranes where they form specific microdomains, named lipid rafts, which mediate specific cell functions. Sphingomyelin (SM) is one of the major sphingolipids. SM and free cholesterol are also two key lipids on the monolayer of plasma lipoproteins, including chylomicron, very low-density
Xian-Cheng, Jiang, Zhiqiang, Li
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Sphingolipids and cholesterol are two lipid partners on cellular membranes where they form specific microdomains, named lipid rafts, which mediate specific cell functions. Sphingomyelin (SM) is one of the major sphingolipids. SM and free cholesterol are also two key lipids on the monolayer of plasma lipoproteins, including chylomicron, very low-density
Xian-Cheng, Jiang, Zhiqiang, Li
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American Journal of Respiratory and Critical Care Medicine, 2008
Abstract Sphingolipids such as sphingosine-1-phosphate (S1P), ceramide, or sphingomyelin are essential constituents of plasma membranes and regulate many (patho)physiological cellular responses inducing apoptosis and cell survival, vascular permeability, mast cell activation, and airway smooth muscle functions.
Stefan, Uhlig, Erich, Gulbins
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Abstract Sphingolipids such as sphingosine-1-phosphate (S1P), ceramide, or sphingomyelin are essential constituents of plasma membranes and regulate many (patho)physiological cellular responses inducing apoptosis and cell survival, vascular permeability, mast cell activation, and airway smooth muscle functions.
Stefan, Uhlig, Erich, Gulbins
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2010
Sphingolipids are a family of ubiquitous membrane components that exhibit multiple functional properties fundamental to cell properties. Sphingolipid transport represents a crucial aspect in the metabolism, signaling and biological role of sphingolipids.
L. Riboni, P. Giussani, P. Viani
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Sphingolipids are a family of ubiquitous membrane components that exhibit multiple functional properties fundamental to cell properties. Sphingolipid transport represents a crucial aspect in the metabolism, signaling and biological role of sphingolipids.
L. Riboni, P. Giussani, P. Viani
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Sphingolipids in Macroautophagy
2008Sphingolipids are constituents of biological membranes. Ceramide and sphingosine 1-phosphate (S1P) also act as second messengers and are part of a rheostat system, in which ceramide promotes cell death and growth arrest, and S1P induces proliferation and maintains cell survival.
G. Lavieu +7 more
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CHEMISTRY OF THE SPHINGOLIPIDES
Canadian Journal of Biochemistry and Physiology, 1956Chemical studies leading to the elucidation of the structures of sphingosine, cerebrosides, sphingomyelin, and cerebroside sulphuric acid are reviewed. The general nature of the complex sphingolipides (ganglioside, hematoside, globoside, strandin, polycerebroside) is discussed.
H E, CARTER, D S, GALANOS, Y, FUJINO
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2022
Asthma is the most prevalent chronic respiratory disease worldwide and the leading serious chronic illness in children. Clinical characteristics are wheezing, reversible airway obstruction, airway inflammation, and airway hyperreactivity. Asthma susceptibility is influenced by genes and environment.
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Asthma is the most prevalent chronic respiratory disease worldwide and the leading serious chronic illness in children. Clinical characteristics are wheezing, reversible airway obstruction, airway inflammation, and airway hyperreactivity. Asthma susceptibility is influenced by genes and environment.
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Biochimica et Biophysica Acta (BBA) - General Subjects, 1999
Many advances in our understanding of fungal sphingolipids have been made in recent years. This review focuses on the types of sphingolipids that have been found in fungi and upon the genes in Saccharomyces cerevisiae, the common baker's yeast, that are necessary for sphingolipid metabolism.
R C, Dickson, R L, Lester
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Many advances in our understanding of fungal sphingolipids have been made in recent years. This review focuses on the types of sphingolipids that have been found in fungi and upon the genes in Saccharomyces cerevisiae, the common baker's yeast, that are necessary for sphingolipid metabolism.
R C, Dickson, R L, Lester
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Sphingolipids in Neuroinflammation
2013Sphingolipids, the main component of cellular membranes, are cellular 'jack-of-all-trades', influencing a variety of functions including signal transduction, cell activation, membrane fluidity and cell-cell interactions.In the last few years, sphingolipids have begun to be investigated in the pathophysiology of major diseases of the brain, e.g ...
Laura, Davies +2 more
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