Identification of a Glycosylation‐Related Gene Prognostic Signature for Non–Small Cell Lung Cancer
The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.A ten‐glycosylation‐related‐gene (GRG) prognostic signature for non‐small cell lung cancer (NSCLC) was constructed using TCGA data. Differentially expressed GRGs were screened and refined by Cox and LASSO regression. The ten‐gene signature (including ADAMTS15, PCSK9, MUC2, and B3GNT3) stratified patients into high‐ and low‐risk groups with distinct ...
Qingtao Zhao +2 more
wiley +1 more source
Lipidomic Remodelling and Low Sperm Quality Associated with High-Fat Diet-Induced Gut Microbial Dysbiosis in Mice. [PDF]
Antioxidants (Basel)Pan M +4 more
europepmc +1 more source
Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy
Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno +3 more
wiley +1 more source
Lifespan trajectories of serum sphingolipids in a clinically healthy Swiss population, towards precision medicine in cardiometabolic health assessment. [PDF]
Commun Med (Lond)Carrard J +9 more
europepmc +1 more source
The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 11, November 2026.ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu +4 more
wiley +1 more source
Ciliary Membrane Lipid Homeostasis in Health and Disease. [PDF]
Adv Sci (Weinh)Huang Z, Liu YY, Sun H, Liu P.
europepmc +1 more source
The Role of Astrocytes in the Inflammatory Response in Neurodiseases
MedComm, Volume 7, Issue 11, November 2026.Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng +3 more
wiley +1 more source
Authors' Reply: Dialysis Dose and Flux as Potential Effect Modifiers of Sphingolipid-Mortality Associations. [PDF]
J Am Soc NephrolLidgard B, Bansal N, Lemaitre R.
europepmc +1 more source
Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy
MedComm, Volume 7, Issue 11, November 2026.Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu +8 more
wiley +1 more source
Sphingolipid and glycerophospholipid profiling in post-acute sequelae of SARS-CoV-2 infection. [PDF]
Sci RepYamamoto S +6 more
europepmc +1 more source