Results 171 to 180 of about 39,549 (288)

Unlocking the therapeutic potential of sphingolipids in wound healing: from molecular mechanisms to clinical applications. [PDF]

Int J Surg
Sujie X, Xinran D, Yixu L, Wei Z, Shuyuan X, Yifan L, Yuntao Y, Bingnan L, Xirui T, Xinya G, Runzhi H, Shizhao J, Zhaofan X.   +12 more
europepmc   +1 more source

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt, Marcel Benkhoff, Nathalie H. Schröder, Hao Hu, Lisa Dannenberg, Petra Keul, Theresia Sarabhai, Kálmán Benedikt Bódis, Tobias Zeus, Philipp Wollnitzke, Malte Kelm, Amin Polzin, Bodo Levkau   +12 more
wiley   +1 more source

Metabolic signatures in sciatic nerve of PMP22 transgenic rats provide insights into the pathogenesis of charcot-marie-tooth disease type 1 A. [PDF]

Sci Rep
Muller A, Grove K, Christen I, Kreider J, Santos C, Hoque S, Bidinosti M, Hatakeyama S, Zhang J.   +8 more
europepmc   +1 more source

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

, 2015
Fikadu Tafesse, Ali Rashidfarrokhi, Florian I. Schmidt, Elizaveta Freinkman, Stephanie K. Dougan, Michael Dougan, Alexandre Esteban, Takeshi Maruyama, Karin Strijbis, Hidde L. Ploegh   +9 more
openalex   +2 more sources

Sphingolipid extracts enhance gene delivery of cationic lipid vesicles into retina and brain

, 2021
Nuseibah Al Qtaish, Idoia Gallego, Ilia Villate-Beitia, Myriam Sainz-Ramos, Gema Martı́nez, Cristina Soto‐Sánchez, Eduardo Fernández, Patricia Gálvez-Martín, Tania B. López-Méndez, Gustavo Puras, José Luís Pedraz   +10 more
openalex   +2 more sources

Beyond nocardioform: Transcriptionally active microbes and host responses in equine mucoid placentitis

Equine Veterinary Journal, EarlyView.
Abstract Background Nocardioform placentitis (NP) is an understudied form of equine placentitis historically attributed to nocardioform bacteria, yet it remains uncertain whether these organisms are the sole pathogens involved. Objectives To elucidate the pathophysiology of NP and the host–pathogen interaction. Study Design In vivo clinical multi‐omics
Machteld van Heule, Margo Verstraete, Jamie Kaj Norris, Kinga Barbara Graniczkowsa, Kirsten E. Scoggin, Hossam El‐Sheikh Ali, Barry A. Ball, Ward De Spiegelaere, Peter Daels, Bart C. Weimer, Pouya Dini   +10 more
wiley   +1 more source

Investigating the Eye as a Biomarker of Gulf War Illness: Sphingolipid and Eicosanoid Composition in Tears and Plasma. [PDF]

Biomolecules
Paule Jimenez LB, Prislovsky A, Parchejo LA, Cabrera K, Nafziger AJ, Stephenson DJ, Chalfant CE, Aenlle K, Klimas N, Tang F, Mandal N, Galor A.   +11 more
europepmc   +1 more source

Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein

The FEBS Journal, EarlyView.
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj, Tadeja Bele, Anastasija Panevska, Gregor Bajc, Jan Kejžar, Miha Bahun, Nataša Poklar Ulrih, Valentina Levak, Matej Skočaj, Larisa Lara Popošek, Peter Veranič, Nataša Resnik, Kristina Sepčić   +12 more
wiley   +1 more source

Dual Biological Potential: Anticancer and Antibacterial Activities of Bis-α, ω-Bifunctional Sphingolipids from the Marine Sponge Oceanapia ramsayi. [PDF]

ChemMedChem
Keneni DA, Njanje I, Kalinski JJ, Isaacs M, Swart T, Davison C, de la Mare JA, Dorrington RA.   +7 more
europepmc   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, EarlyView.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source