Results 141 to 150 of about 50,283 (222)

Lactose‐Derived Carbohydrates Induce Sexually Dimorphic Nutritional Programming Effects on Lifespan in Drosophila melanogaster

Aging Cell, Volume 25, Issue 3, March 2026.
Early‐life co‐consumption of galactose and glucose (hydrolyzed lactose) programs Drosophila melanogaster lifespan in a sex‐specific manner. Particularly, the co‐consumption of galactose and glucose programs extended lifespan when female flies were challenged by obesogenic diets later in life, and this is concomitant with remodeling of lipid metabolism,
Peixin Sun, Shiying Shao, Robin W. Creemers, Anna F. Bekebrede, Jing Tang, Steven Driever, Jaap Keijer, Evert M. van Schothorst   +7 more
wiley   +1 more source

Critique of a Radically New Model for Plasma Membrane Bilayer Organization. [PDF]

Bioessays
Lange Y, Steck TL.
europepmc   +1 more source

Regulation of Lipid Dysmetabolism and Neuroinflammation Progression Linked With Alzheimer's Disease Through Modulation of Dgat2

Aging Cell, Volume 25, Issue 3, March 2026.
Drosophila and mouse models of Alzheimer's disease exhibit lipid accumulation and neuroinflammation, leading to progressive impairments in memory, locomotion, sleep, circadian rhythms, and synaptic integrity. Knockdown of Dgat2 reduces lipid accumulation and neuroinflammatory signaling, rescuing these deficits and highlighting a conserved, crossspecies
Archana Yadav, Xiaosen Ouyang, Morgan Barkley, John C. Watson, Kishore Madamanchi, Josh Kramer, Jianhua Zhang, Girish C. Melkani   +7 more
wiley   +1 more source

Dietary Choline Intake During Pregnancy and Congenital Heart Defects in a Chinese Population. [PDF]

Nutrients
Li YH, Xiao Z, Guo R, Rekemubieke B, Hu W, Liu X, Yang J.   +6 more
europepmc   +1 more source

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2175-2182, March 2026.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt, Marcel Benkhoff, Nathalie H. Schröder, Hao Hu, Lisa Dannenberg, Petra Keul, Theresia Sarabhai, Kálmán Benedikt Bódis, Tobias Zeus, Philipp Wollnitzke, Malte Kelm, Amin Polzin, Bodo Levkau   +12 more
wiley   +1 more source

Circulating metabolites on dental caries risk: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Shi P, Liu X, Lei F, Hu Z, Xu Z.
europepmc   +1 more source

Educational Value and Reliability of Exosome Therapy Videos on YouTube: A Cross‐Sectional Quality Assessment

International Wound Journal, Volume 23, Issue 3, March 2026.
ABSTRACT Exosome therapy has emerged in recent years as a promising acellular approach for the treatment of tissue regeneration and wound healing. Initial preclinical investigations have demonstrated accelerated fibroblast proliferation, improved angiogenesis and reduced scar formation.
Emrah Işıktekin, Salih Kılıç
wiley   +1 more source

Immune Microenvironment Dynamics and Therapeutic Targets in GIST Revealed by Multi‐Omics and Functional Validation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.
ABSTRACT The tumour immune microenvironment (TIME) significantly influences the progression and treatment response of gastrointestinal stromal tumours (GIST), but the causal mechanisms and therapeutic targets remain incompletely understood. We integrated multi‐omics analyses, including Mendelian randomization analysis of 731 immune cell phenotypes to ...
Xingyuan Li, Jun Xiang, Zewen Chang, Qingchao Tang   +3 more
wiley   +1 more source

Altered Sphingolipids, Glycerophospholipids, and Lysophospholipids Reflect Disease Status in Idiopathic Steroid-Sensitive Nephrotic Syndrome in Children: A Non-Targeted Metabolomic Study. [PDF]

Cells
Kanai T, Ogiso H, Aoyagi J, Kurosaki M, Maru T, Ishii M, Tanimoto K, Yoshino M, Yamashita Y, Tajima T, Nagai R, Aizawa K.   +11 more
europepmc   +1 more source

Notizen: Die Biosynthese des Sphingomyelin / The Biosynthesis of Sphingomyelin

Zeitschrift für Naturforschung B, 1972
H. Diringer, W. D. Marggraf, M. A. Koch, F. A. Anderer   +3 more
openaire   +1 more source