Mycoplasma pneumoniae pathogenesis relies on its CARDS toxin, which initiates cell binding and subsequent uptake by exploiting sphingomyelin, a key phospholipid found in the host plasma membrane. Maximal cellular entry and full cytotoxic effects are achieved through a synergistic mechanism that involves interaction with the protein coreceptor annexin ...
Alejandra M. Kirkpatrick +1 more
wiley +1 more source
Circulating Lipoprotein Sphingolipids in Chronic Kidney Disease with and without Diabetes
Abnormalities of sphingolipid metabolism play an important role in diabetes. We compared sphingolipid levels in plasma and in isolated lipoproteins between healthy control subjects and two groups of patients, one with chronic kidney disease without ...
Maria F. Lopes-Virella +4 more
doaj +1 more source
Transient domain formation in membrane-bound organelles undergoing maturation
The membrane components of cellular organelles have been shown to segregate into domains as the result of biochemical maturation. We propose that the dynamical competition between maturation and lateral segregation of membrane components regulates domain
Dmitrieff, Serge, Sens, Pierre
core +3 more sources
ABSTRACT Brain development is an ongoing process that occurs throughout the first 1000 days of life (conception until 2 years) and proceeds throughout childhood, adolescence and up until early adulthood. Adequate nutrient intakes are crucial for both neurodevelopment inside the womb and critical life‐stages thereafter when the brain continues to grow ...
Emma J. Derbyshire
wiley +1 more source
Review and targeted lipidomic biomarkers in atherosclerosis
Ischemic cardiovascular events (ischemic stroke, myocardial infarction) are the most common complications of cardiovascular diseases. One of the leading mechanisms of these complications is atherosclerosis.
A. A. Lomonosova +12 more
doaj +1 more source
Application of electrospray mass spectrometry to the analysis of lipids : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Food Technology at Massey University [PDF]
This work investigated the application of electrospray mass spectrometry (MS) to the elucidation of lipid structure, especially related to milkfat. This was the first time that the instrument in our laboratory had been used for this purpose.
Norris, Carmen
core
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano +2 more
wiley +1 more source
Urinary lipid metabolites and progression of kidney disease in individuals with type 2 diabetes
ObjectiveA substantial proportion of individuals with type 2 diabetes (T2D) experience a fast decline (FD) in kidney function, a high-risk phenotype not reliably identified by current clinical markers.
Yu Xiao +6 more
doaj +1 more source
TaRIP2 Positively Regulates Wheat Pollen Wall Formation Through MYB80‐Controlled Lipid Metabolism
ABSTRACT Male‐sterile genes and mutants are critical for hybrid seed production in monocotyledonous crops. Lipids are essential structural components of male reproductive organs, such as the anther and pollen. Here, we show that the pollen‐preferential gene TaRIP2 is essential for wheat anther development and pollen formation. RT‐qPCR analysis revealed
Ran Han +14 more
wiley +1 more source
Deficiency of sphingomyelin synthase 2 prolongs survival by the inhibition of lymphoma infiltration through ICAM‐1 reduction [PDF]
Makoto Taniguchi +11 more
openalex +1 more source

