Results 171 to 180 of about 81,593 (273)
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou +5 more
wiley +1 more source
Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian +5 more
wiley +1 more source
Effects of the Eukaryotic Pore-Forming Cytolysin Equinatoxin II on Lipid Membranes and the Role of Sphingomyelin [PDF]
, 2003 Boyan B. Bonev +5 more
openalex +1 more source
Advanced Therapeutics, Volume 9, Issue 1, January 2026.A bi‐functional liposomal system is developed to enhance melanoma therapy, combining mApoE‐mediated targeting of LDLR‐expressing tumor cells with MMP2‐responsive drug release. Loaded with Pimasertib, the liposomes improve intracellular delivery, reduce melanoma viability, and inhibit 3D spheroid growth and invasiveness.
Antonio Renda +14 more
wiley +1 more source
Validity of the Lecithin/ Sphingomyelin (L/S) Ratio for Amniotic Fluid Containing Blood [PDF]
, 1972 Rita Bryan
openalex +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.Women with overweight or obesity follow intended isocaloric early and late time‐restricted eating (TRE) in a crossover trial. Shotgun plasma lipidomics reveals no significant differences between interventions, but identify pronounced lipid changes—including reductions in ceramides and phosphatidylcholines—within the early TRE.
Kristof Szekely +15 more
wiley +1 more source
Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision [PDF]
, 2018 Adak, Sangeeta +11 more
core +2 more sources
Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in Solution
Advanced Science, Volume 13, Issue 3, 14 January 2026.Partial Replacement of phospholipid lipid by cationic lipid improves storage stability of commercial mRNA LNPs by stabilizing their internal microstructure. Abstract Messenger RNA lipid nanoparticles (mRNA‐LNPs) have achieved remarkable success in clinical vaccination efforts to curb the COVID‐19 pandemic, and have attracted tremendous interest from ...
Rui Chen +8 more
wiley +1 more source