Results 91 to 100 of about 50,070 (158)
Sequence analysis reveals extensive polymorphism and evidence of deletions within the E2 glycoprotein gene of several strains of murine hepatitis virus. [PDF]
, 1989 Direct RNA sequence analysis of the E2 gene of wild-type MHV-4 and of neutralization resistant, neuroattenuated variants has identified a polymorphic region with respect to deletions.
Buchmeier, MJ, Gallagher, TM, Parker, SE
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Architects of infection: A structural overview of SARS-related coronavirus spike glycoproteins
VirologyThe frequency of zoonotic viral emergence within the Coronaviridae family highlights the critical need to understand the structural features of spike proteins that govern viral entry and host adaptation. Investigating the structural conservation and variation in key regions of the spike protein-those involved in host range, binding affinity, viral ...
Francesca R. Hills +2 more
openaire +2 more sources
Novel Wide‐Spectrum Virucidal Lipid Nanoparticles
Small, Volume 22, Issue 7, 2 February 2026.POSTAN is a novel broad‐spectrum antiviral nanoparticle that combines safety with potent virucidal activity. Composed of biocompatible lipids, it mimics heparan sulfate proteoglycans and lipid rafts exploited by viruses, thereby dismantling viral envelopes and blocking replication.
Yugo Araújo Martins +10 more
wiley +1 more source
Nucleotide Sequence of the Gene Encoding the Spike Glycoprotein of Human Coronavirus HCV 229E
Journal of General Virology, 1990 The gene encoding the spike glycoprotein of the human coronavirus HCV 229E has been cloned and sequenced. This analysis predicts an S polypeptide of 1173 amino acids with an Mr of 128,600. The polypeptide has 30 potential N-glycosylation sites. A number of structural features typical of coronavirus S proteins can be recognized, including a signal ...
T, Raabe, B, Schelle-Prinz, S G, Siddell
openaire +2 more sources
Virology, 2007 The SARS-coronavirus (SARS-CoV) is the etiological agent of the severe acute respiratory syndrome (SARS). The SARS-CoV spike (S) glycoprotein mediates membrane fusion events during virus entry and virus-induced cell-to-cell fusion. The cytoplasmic portion of the S glycoprotein contains four cysteine-rich amino acid clusters.
Petit, Chad M. +6 more
openaire +2 more sources
Protection of Mice from Lethal Coronavirus MHV-A59 Infection by Monoclonal Affinity-Purified Spike Glycoprotein [PDF]
, 1990 Numerous studies have provided indirect evidence that the spike glycoprotein of coronaviruses (E2 or S) bears determinants for pathogenesis and the induction of protective immunity. In order to directly evaluate its immunogenicity, the E2 glycoprotein of the murine hepatitis virus, strain A59, was purified by immunoaffinity chromatography.
C, Daniel, P J, Talbot
openaire +2 more sources
Journal of General Virology, 1996 The full-length spike (S) gene of porcine respiratory coronavirus (PRCV) was inserted into the genome of human adenovirus type 5 downstream of the early transcription region 3 promoter. The recombinant virus replicated in cultures of the swine testicle ST cell line and directed the synthesis of S antigen with a maximum yield of approximately 26 ...
P, Callebaut, L, Enjuanes, M, Pensaert
openaire +2 more sources
Identification Of Infectious Bronchitis Virus Isolates From Malaysia [PDF]
, 2007 Infectious bronchitis (IB) is a highly contagious respiratory, urogenital and reproduction disease of chickens and it is distributed worldwide. The disease is caused by infectious bronchitis virus (IBV).
A. Talip, Balkis
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Pathogenesis of feline enteric coronavirus infection. [PDF]
, 2008 Fifty-one specific pathogen-free (SPF) cats 10 weeks to 13 years of age were infected with a cat-to-cat fecal-oral passed strain of feline enteric coronavirus (FECV). Clinical signs ranged from unapparent to a mild and self-limiting diarrhea. Twenty-nine
Allen, Claire E +2 more
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Troubleshooting methods for the generation of novel pseudotyped viruses [PDF]
, 2016 A pseudotyped virus (PV) is a virus particle with an envelope protein originating from a different virus. The ability to dictate which envelope proteins are expressed on the surface has made pseudotyping an important tool for basic virological studies ...
Daly, Janet M. +6 more
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