Results 71 to 80 of about 50,070 (158)

Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia [PDF]

, 2018
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Alfaraj, Sarah H., Altuwaijri, Talal A., Memish, Ziad A.   +3 more
core   +1 more source

Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology

Journal of Animal Ecology, EarlyView.
Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley, Caylee A. Falvo, Chris K. Grant, Benny Borremans, Tamika J. Lunn, Manuel Ruiz‐Aravena, Evelyn Benson, Clifton D. McKee, Daniel J. Becker, Devin N. Jones, Trenton Bushmaker, Y. Tina Yu, Michelle Michie, Adrienne S. Dale, Lianying Yan, Spencer L. Sterling, Christopher C. Broder, Laura B. Goodman, Rasa Petraityte‐Burneikiene, Eric D. Laing, Ina L. Smith, Vincent J. Munster, Agnieszka Rynda‐Apple, Alison J. Peel, Raina Plowright   +24 more
wiley   +1 more source

Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein

Virology, 2014
The recent identification of a novel human coronavirus responsible of a SARS-like illness in the Middle-East a decade after the SARS pandemic, demonstrates that reemergence of a SARS-like coronavirus from an animal reservoir remains a credible threat. Because SARS is contracted by aerosolized contamination of the respiratory tract, a vaccine inducing ...
Escriou, Nicolas, Callendret, Benoît, Lorin, Valérie, Combredet, Chantal, Marianneau, Philippe, Février, Michèle, Tangy, Frédéric   +6 more
openaire   +2 more sources

Transmissible gastroenteritis virus: Identification of M protein-binding peptide ligands with antiviral and diagnostic potential [PDF]

, 2013
The membrane (M) protein is one of the major structural proteins of coronavirus particles. In this study, the M protein of transmissible gastroenteritis virus (TGEV) was used to biopan a 12-mer phage display random peptide library.
Ren, Xiaofeng, Sestak, Karol, Suo, Siqingaowa, Zarlenga, Dante S., Zou, Hao   +4 more
core   +1 more source

Single-domain antibodies and their formatting to combat viral infections [PDF]

, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies, De Vlieger, Dorien, Rossey, Iebe, Saelens, Xavier, Schepens, Bert   +4 more
core   +2 more sources

Are Tetrapleura tetraptera Phytochemicals Druggable Against SARS‐CoV‐2 Papain‐Like Protein? A Computational Approach

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
SARS‐CoV2 Omicron and its substrains are still a critical global health issue and extremely contagious, even with widespread vaccination efforts. Hospitalizations and mortality rates linked to these variants are still prevalent. Current therapeutic options face challenges, including low effectiveness, suboptimal pharmacokinetics, and drug resistance ...
Frank Eric Tatsing Foka, Hazel Tumelo Mufhandu   +1 more
wiley   +1 more source

Properties of Coronavirus IBV After Removal of the S1 Subunit of the Spike Glycoprotein [PDF]

, 1987
Our recent investigations of avian infectious bronchitis virus (IBV) have concentrated on the biological properties of the spike (S) glycoprotein. Previously we showed that the mature S is derived by cleavage of a precursor glycoprotein to yield two glycopolypeptides, S1 and S2 of approximately 514 and 625 amino acid residues respectively1.
D, Cavanagh, P, Davis
openaire   +2 more sources

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance Middle East respiratory syndrome coronavirus (MERS-CoV) recurrently infects humans from its dromedary camel reservoir, causing severe respiratory disease with an ∼35% fatality rate. The virus binds to the dipeptidyl peptidase 4 (DPP4) entry receptor on respiratory epithelial cells via its spike protein.
Li, Wentao; Hulswit, Ruben J. G.; Widjaja, Ivy; Raj, V. Stalin; McBride, Ryan; Peng, Wenjie; Widagdo, W.; Tortorici, M. Alejandra; Van Dieren, Brenda; Lang, Yifei; van Lent, Jan W. M.; Paulson, James C.; de Haan, Cornelis A. M.; de Groot, Raoul J.; van Kuppeveld, Frank J. M.; Haagmans, Bart L.; Bosch, Berend-Jan   +17 more
openaire   +4 more sources

Differences in virus receptor for type I and type II feline infectious peritonitis virus. [PDF]

, 1998
Feline infectious peritonitis viruses (FIPVs) are classified into type I and type II serogroups. Here, we report that feline aminopeptidase N (APN), a cell-surface metalloprotease on the intestinal, lung and kidney epithelial cells, is a receptor for ...
Hohdatsu, T, Izumiya, Y, Kida, K, Koyama, H, Yokoyama, Y   +4 more
core  

A fusion peptide in the spike protein of MERS coronavirus [PDF]

, 2019
Coronaviruses represent current and emerging threats for many species, including humans. Middle East respiratory syndrome-related coronavirus (MERS-CoV) is responsible for sporadic infections in mostly Middle Eastern countries, with occasional transfer ...
Benjamin W. Neuman, Earp, Entedar A. J. Alsaadi, Hu, Ian M. Jones   +4 more
core   +1 more source