Results 201 to 210 of about 542,273 (348)

DYN-1 regulates SPD-2 and PLK-1 localization and mitotic spindle pole organization. [PDF]

open access: yesMol Biol Cell
Dierlam C   +5 more
europepmc   +1 more source

Expanding the Genotype–Phenotype Correlation of Marden–Walker Syndrome due to PIEZO2 Gene Variants: A Case Report From Brazil

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Marden–Walker syndrome (MWS; OMIM 248700) is an extremely rare congenital disorder characterized by multiple joint contractures, craniofacial dysmorphism, neurological abnormalities, and multisystem involvement. Although historically diagnosed on clinical grounds, only a few cases have been molecularly confirmed.
Guilherme Sotto Battiston   +35 more
wiley   +1 more source

Dissipatively Fueled Unidirectionally Communicating DNA Circuits That Control Biocatalysis

open access: yesAngewandte Chemie, EarlyView.
Unidirectionally communicating, out‐of‐equilibrium DNA circuits are used to control enzyme activity. Transient DNAzyme activation generates fuel for temporal trypsin activation. Cyclic fuel‐driven hybridization and exonuclease‐mediated reset enable precise control over lifetimes, which is analyzed using combined experimental and computational ...
Philippe Jung   +6 more
wiley   +2 more sources

Metformin enhances external urethral sphincter integrity and restores continence via AMPK activation in a rat model of stress urinary incontinence

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The pathogenesis of stress urinary incontinence (SUI) is intimately associated with injury to the external urethral sphincter (EUS). In this study, we established an SUI model induced by double vaginal distension and demonstrated that metformin treatment activated the AMPK signaling in the EUS tissue.
Yuting Xu   +7 more
wiley   +1 more source

Deubiquitinase USP8 regulates the spindle assembly checkpoint in oocytes. [PDF]

open access: yesSci Adv
Zhou 周长银 C   +7 more
europepmc   +1 more source

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.

open access: yesScience, 1999
T. Mayer   +5 more
semanticscholar   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

An Integrated Flexible Bioelectrical and Biochemical Monitoring System Based on Spindle-Structured Directional Sweat-Pumping Nanomesh. [PDF]

open access: yesNanomicro Lett
Wu J   +18 more
europepmc   +1 more source

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