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, 2023 Yaojing Shi, Hua Zhao, Yufen Zhao
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Ligandos multidiana relacionados con productos naturales para el tratamiento potencial de enfermedades neurodegenerativas [PDF]
, 2020 Neurodegenerative diseases are characterized by the loss of neurons in the brain and/or spinal cord and constitute one of the most important health problems worldwide.
Cores Esperón, Ángel
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Morphological Profiling Identifies the Motor Protein Eg5 as Cellular Target of Spirooxindoles [PDF]
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Design, synthesis, and antitumor activity of novel dispiro[oxindole-cyclohexanone]-pyrrolidines [PDF]
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Beilstein Journal of Organic Chemistry, 2010 The synthesis of C3-carbocyclic spirooxindoles was realized by way of an intramolecular [2 + 2] cycloaddition reaction between a vinylidene indolin-2-one and an alkyne.
Kay M. Brummond, Joshua M. Osbourn
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A novel alpha‐amylase inhibitor‐based
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Green Synthesis of Spirooxindoles via Lipase-Catalyzed One-Pot Tandem Reaction in Aqueous Media [PDF]
, 2023 Yong Tang +7 more
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Stereocontrolled Synthesis of Spirooxindoles through Lewis Acid-Promoted [5 + 2]-Annulation of Chiral Silyl Alcohols [PDF]
, 2009 Yun Zhang, James S. Panek
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Efficient Synthesis of Tetrahydrofuran Spirooxindoles via One-Pot Reaction [PDF]
, 2020 Xin Guo +5 more
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The therapeutic potential of small molecules p53-MDM protein-protein interaction inhibitors [PDF]
, 2016 Tese de mestrado, Ciências Biofarmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2016Ao longo dos anos, vários estudos científicos têm comprovado a importância da proteína supressora de tumor p53 na homeostase celular.
Nunes, Rute Cláudia Correia Sacadura
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