Results 101 to 110 of about 2,755 (155)

Construction of Spirooxindole Skeleton Through Intramolecular Dieckmann Cyclization

Natural Products and Bioprospecting, 2017
A highly efficient and direct approach was developed to construct the structurally diverse spirooxindole skeleton, which is an important basic motif in natural products.
Ting Wu, Zhiqiang Pan, Chengfeng Xia
doaj   +1 more source

An N‐Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones [PDF]

, 2012
Julien Dugal‐Tessier, Elizabeth A. O’Bryan, Thomas B. H. Schroeder, Daniel T. Cohen, Karl A. Scheidt   +4 more
openalex   +1 more source

SYNTHESIS, SPECTRAL CHARACTERIZATION, AND ANTIPROLIFERATIVE ACTIVITY OF DISPIROPYRROLIDINES CONTAINING 2-THIOXOTHIAZOLIDIN-4-ONE NUCLEUS [PDF]

, 2019
Objective: Spiro compounds are present in nature, endowed with deep biological activities. Heterocyclic compounds with a pyrrolidine scaffold are one of the paradigms of organic chemistry that exhibits a wide variety of properties and biological ...
KAVERI SUNDARAM, MALARVIZHI, THALIGAI SUBRAMANIAN, SIVAGNANAM JAYASURIYA, STEPHENKUMAR CELESTINA   +3 more
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Comparative Investigation of Key Biosynthetic Transformations in Fungal Indole Alkaloid Natural Product Pathways. [PDF]

, 2015
My dissertational research has focused on the elucidation of three key biosynthetic steps involved in the formation of fungal indole alkaloid natural products. Beginning with the comparative analysis of four assembled putative gene clusters, we performed
Tran, Hong T.
core  

Complete transfer of chirality in an intramolecular, thermal [2 + 2] cycloaddition of allene-ynes to form non-racemic spirooxindoles

Beilstein Journal of Organic Chemistry, 2011
A thermal [2 + 2] cycloaddition reaction of allene-ynes has been used to transform chiral non-racemic allenyl oxindoles into chiral non-racemic spirooxindoles containing an alkylidene cyclobutene moiety.
Kay M. Brummond, Joshua M. Osbourn
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Formation of diverse polycyclic spirooxindoles via three-component reaction of isoquinolinium salts, isatins and malononitrile [PDF]

, 2017
Jing Sun, Guo‐Liang Shen, Ying Huang, Chao‐Guo Yan   +3 more
openalex   +1 more source

Stereoselective synthesis, structure and DFT studies on fluoro- and nitro- substituted spirooxindole-pyrrolidine heterocyclic hybrids

, 2021
Abdulrahman I. Almansour, Natarajan Arumugam, Saied M. Soliman, Bellie Sundaram Krishnamoorthy, Jean‐François Halet, R. Vishnupriya, J. Suresh, Dhaifallah M. Al‐thamili, Faiz A. Al‐aizari, Raju Suresh Kumar   +9 more
openalex   +2 more sources

DABCO-promoted highly diastereo- and regioselective construction of C-3 functionalized spirooxindoles via [3 + 2] cycloaddition of 2-aryl/heteroarylidene-1H-indene-1,3(2H)-diones with N-2,2,2-trifluoroethylisatin ketimines at ambient conditions

, 2022
Madavi S. Prasad, Sankar Bharani, Syed Mastan Sharief, Mudavath Ravi, Murugesan Sivaprakash, Biplob Borah, L. Raju Chowhan   +6 more
openalex   +2 more sources

Elucidation of the biogenesis of the paraherquamides, malbrancheamides, citrinalins, and brevianamides [PDF]

, 2019
2019 Summer.Includes bibliographical references.Various fungi of the genera Aspergillus, Penicillium and Malbranchea produce prenylated indole alkaloids that possess a bicyclo[2.2.2]diazaoctane ring system and a variety of biological activities such as ...
Klas, Kimberly R.
core  

Design, stereoselective synthesis and anticancer efficacy of a new class of functionalized pyrrolizidine heterocyclic hybrids

Journal of King Saud University: Science
Eight new functionalized spirooxindole-pyrrolizidine heterocyclic hybrids has been obtained from N-pyridinylmethyl-bisarylmethylidene-pyridinones, Isatin and L-Proline by a multi-component cycloaddition reaction.
Raju Suresh Kumar, Dhaifallah M. Al-thamili, Khloud Ibrahim Al-Shemaimari, Faruq Mohammad, Mohamad Altaf, Rashid Ayub   +5 more
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