Results 161 to 170 of about 2,159 (193)

Heterogeneous organocatalysis: the proline case. [PDF]

open access: yesRSC Adv
de Carvalho GSG   +3 more
europepmc   +1 more source

Dynamic radical recombination enabling stereodivergent construction of spirocycles with nonadjacent stereocenters. [PDF]

open access: yesNat Commun
Sun Z   +12 more
europepmc   +1 more source

Enantioselective Construction of Spirooxindole-Fused Cyclopentanes

The Journal of Organic Chemistry, 2021
The present study reports an asymmetric organocatalytic cascade reaction of oxindole derivates with α,β-unsaturated aldehydes efficiently catalyzed by simple chiral secondary amine. Spirooxindole-fused cyclopentanes were produced in excellent isolated yields (up to 98%) with excellent enantiopurities (up to 99% ee) and moderate to high ...
Vojtěch Dočekal   +7 more
openaire   +2 more sources

A New Route to Spirooxindoles

Organic Letters, 2000
[reaction: see text]Reaction of indole amides 5 with tributylstannane gave spiroindolenines 9 which are readily converted into spiropyrrolidinyloxindoles. This tricyclic system is found in a number of interesting natural products.
S T, Hilton   +3 more
openaire   +2 more sources

Spirooxindoles as Potential Pharmacophores

Mini-Reviews in Medicinal Chemistry, 2017
The spiroindole heterocyclic scaffold is found in many natural products and has been identified as an important bioactive agent. Over the past few decades, various spiroindole-containing compounds have been reported to possess biological properties and hence found in the structure of many synthetic pharmaceuticals.
Siva S, Panda   +3 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy