Results 141 to 150 of about 4,752 (252)

Spirooxindoles derivatives as novel inhibitors of the respiratory syncytial virus [PDF]

open access: yes, 2017
Respiratory Syncytial Virus (RSV) is an important pathogen that affects the lower respiratory track resulting in hospitalisation in infants and young children and is a significant cause of morbidity and mortality in the elderly and immunocompromised ...
Paradowski, Michael
core  

Titanium(IV)-Catalyzed Stereoselective Synthesis of Spirooxindole-1-pyrrolines

open access: bronze, 2014
Joseph J. Badillo   +3 more
openalex   +1 more source

Quantitative structure-activity relationship and ADME prediction studies on series of spirooxindoles derivatives for anti-cancer activity against colon cancer cell line HCT-116

open access: yesHeliyon
Forty-one derivatives of spirooxindoles, active against HCT-116 colon cancer cells, underwent pharmacophore-based 3D-QSAR analysis to understand their correlation with anti-cancer activity. The study identified a seven-point pharmacophore model (ADHHRRR1)
Sukhmeet Kaur   +4 more
doaj  

Combined Scaffold Evaluation and Systems‐Level Transcriptome‐Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes

open access: green, 2019
Kevin X. Rodriguez   +11 more
openalex   +2 more sources

Cytotoxic Activity of Some Spirooxindole-4H-pyran Derivatives

open access: bronze, 2019
Zeinab Faghih   +3 more
openalex   +1 more source

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