Results 91 to 100 of about 11,943 (150)

Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast

, 2018
Triterpene cyclases catalyze the first committed step in triterpene biosynthesis, by forming mono- to pentacyclic backbone structures from oxygenated C30 isoprenoid precursors.
Khakimov, Bekzod, Souza de Oliveira, Louisi, Almeida, Aldo, Lota, Frederic, de Oliveira, Louisi Souza, Pollier, Jacob, Bassard, Jean-Etienne, Lazaridi, Eleni, Ntallas, Georgios, Bak, Soren, Michoux, Franck, Bak, Søren, Arendt, Philipp, Dong, Lemeng, Goossens, Alain   +14 more
core   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Biochemical characterization of terbinafine-resistant Trichophyton rubrum isolates

, 2004
We investigated the biochemical basis for resistance in six sequential clinical isolates of Trichophyton rubrum, from the same patient, which exhibited high-level primary resistance to terbinafine.
Ghannoum, M. A., Favre, B., Ryder, N. S.
core   +1 more source

Inhibition of squalene epoxidase linking with PI3K/AKT signaling pathway suppresses endometrial cancer. [PDF]

Cancer Sci, 2023
Ma L, Huang W, Liang X, Bai G, Wang X, Jiang H, Xin Y, Hu L, Chen X, Liu C.   +9 more
europepmc   +1 more source

High-level recombinant production of squalene using selected Saccharomyces cerevisiae strains

, 2018
For recombinant production of squalene, which is a triterpenoid compound with increasing industrial applications, in microorganisms generally recognized as safe, we screened Saccharomyces cerevisiae strains to determine their suitability. A strong strain
Eui-Sung Choi, Eui Sung Choi, Sung Hwa Seo, Hongweon Lee, Jong Yun Han, Hong-Weon Lee, Jae Myeong Song, Sung-Hwa Seo   +7 more
core   +1 more source

Functional Characterization of Squalene Epoxidases from Siraitia grosvenorii

Plants
The medicinal plant Siraitia grosvenorii produces sweet-tasting cucurbitane-type mogrosides from the atypical triterpenoid precursor 2,3,22,23-dioxidosqualene (SDO), rather than the conventional 2,3-oxidosqualene (SQO).
Huan Zhao, Ze Song, Xuan Liu, Shukun Gong, Qi Tang, Changli Liu, Yifeng Zhang, Xianan Zhang, Haiyun Gao, Wei Gao, Yating Hu, Luqi Huang   +11 more
doaj   +1 more source

Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans

, 2005
Objectives: Functional characterization of the erg1 mutant of ergosterol biosynthesis of Candida albicans. Methods: We disrupted the ERG1 gene of C. albicans, which encodes squalene epoxidase (EC 1.14.99.7).
Ernst, Joachim F., Ritu Pasrija, Krishnamurthy, Shankarling, Tulika Prasad, Pasrija, Ritu, Prasad, Tulika, Shankarling Krishnamurthy, Joachim F. Ernst, Prasad, Rajendra   +8 more
core   +1 more source

Inhibition of KDM4A restricts SQLE transcription and induces oxidative stress imbalance to suppress bladder cancer

Redox Biology
In clinical practice, the limited efficacy of standard comprehensive therapy for advanced bladder cancer and the lack of targeted treatment options are well recognized.
Jiapeng Zhang, Hang Xu, Yirui He, Xiaonan Zheng, Tianhai Lin, Lu Yang, Ping Tan, Qiang Wei   +7 more
doaj   +1 more source

Comparative Molecular Field Analysis of Fungal Squalene Epoxidase Inhibitors

, 2016
Comparative molecular field analysis (CoMFA) of fungal squalene epoxidase inhibitors exhibiting antifungal activity reported in terms of minimum inhibitory concentration (MIC) was performed.
Vijay M. Gokhale (3023235), Vithal M. Kulkarni (3021603)   +1 more
core   +1 more source

Novel Insight into the Role of Squalene Epoxidase (SQLE) Gene in Determining Milk Production Traits in Buffalo. [PDF]

Int J Mol Sci, 2023
Chen C, Hu X, Ahmad MJ, Niu K, Ye T, Liang A, Yang L.   +6 more
europepmc   +1 more source