Results 101 to 110 of about 11,943 (150)

Epigallocatechin gallate lowers the serum lathosterol to squalene ratio, a novel index of cholesterol synthesis, in the hypercholesterolaemic rabbit model

, 2007
Background – Epigallocatechin gallate (EGCG) is a major green tea catechin which is related to the reduction ofplasma cholesterol in animal models possibly through inhibition of cholesterol synthesis. Consistent with this, invitro studies have shown EGCG
Roach, Paul D., NAUMOVSKI, Nenad; id_orcid   +1 more
core   +1 more source

Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with p53 mutation and elevated c-MYC expression. [PDF]

Int J Biol Sci, 2023
Du Y, Rokavec M, Hermeking H.
europepmc   +1 more source

Lipid saturation induces degradation of squalene epoxidase for sterol homeostasis and cell survival. [PDF]

Life Sci Alliance, 2023
Huang LJ, Chen RH.
europepmc   +1 more source

A small H₂O-soluble ingredient of royal jelly lower cholesterol levels in liver cells by suppressing squalene epoxidase. [PDF]

Heliyon, 2022
Wang C, Jiang ZY, Wang J, Lou JX, Nian YY, Liu LX, Dang T, Meng XM.   +7 more
europepmc   +1 more source

Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis. [PDF]

Gut, 2022
Li C, Wang Y, Liu D, Wong CC, Coker OO, Zhang X, Liu C, Zhou Y, Liu Y, Kang W, To KF, Sung JJ, Yu J.   +12 more
europepmc   +1 more source

Squalene synthase predicts poor prognosis in stage I-III colon adenocarcinoma and synergizes squalene epoxidase to promote tumor progression. [PDF]

Cancer Sci, 2022
Jiang H, Tang E, Chen Y, Liu H, Zhao Y, Lin M, He L.   +6 more
europepmc   +1 more source

Antifungal Susceptibility and Mutations in the Squalene Epoxidase Gene in Dermatophytes of the Trichophyton mentagrophytes Species Complex. [PDF]

Antimicrob Agents Chemother, 2021
Kong X, Tang C, Singh A, Ahmed SA, Al-Hatmi AMS, Chowdhary A, Nenoff P, Gräser Y, Hainsworth S, Zhan P, Meis JF, Verweij PE, Liu W, de Hoog GS.   +13 more
europepmc   +1 more source

Squalene epoxidase expression is associated with breast tumor progression and with a poor prognosis in breast cancer. [PDF]

Oncol Lett, 2021
Kim NI, Park MH, Kweon SS, Cho N, Lee JS.   +4 more
europepmc   +1 more source

Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling. [PDF]

Cancer Commun (Lond), 2021
He L, Li H, Pan C, Hua Y, Peng J, Zhou Z, Zhao Y, Lin M.   +7 more
europepmc   +1 more source

Multi-cohort analysis and experimental study on the function of squalene epoxidase as a ferroptosis inhibitor in HCC. [PDF]

BMC Cancer
Yang X, Wu Y, Zhang Q, Zhou Y, Chang S, Zhang C, Liu D.   +6 more
europepmc   +1 more source