Results 81 to 90 of about 11,943 (150)

Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

Medical Mycology Case Reports
We identified 5 Thai patients diagnosed with Trichophyton indotineae infection after screening of patients with culture results consistent with Trichophyton mentagrophytes complex who had negative urease test and confirmed by molecular analysis in DNA ...
Sutsarun Prunglumpoo, Kunyanut Krongboon, Klaichan intarachaieua, Anzawa Kazushi, Thareena Bunnag, Wattamon Paunrat, Wanchanida komkhong   +6 more
doaj   +1 more source

Analysis of sterol biosynthesis genes from the genome information of Medaka Oryzias latipes The estimation of gene structure of Squalene epoxidase [PDF]

, 2013
The gene structure of Medaka Oryzias latipes Squalene epoxidase was investigated through BLAST search by comparison of National BioResource Project, Medaka genome database, with the cDNA base sequences of Homo sapiens and Danio rerio in order to ...
NISHINO, Hideaki, タナカ, サトシ, TANAKA, Satoshi, nikA_ediH-ph24_D, 200901029431396951, 2807, 6407, 40198487, ニシノ, ヒデアキ, 田中, 哲, 西野, 秀昭   +10 more
core   +1 more source

Antidermatophytic action of new 1-naphthylmethyl and benzo[b]thiophen-7-ylmethyl hydrazones related to inhibitors of squalene epoxidase.

, 2000
Two series of hydrazonic compounds related to main classes of inhibitors of fungal squalene epoxidase (SE) were designed and prepared on the hypothesis of a pharmacophoric model. The antifungal activity of the new compounds was evaluated in vitro against
Pau A, Carlone N, Roana J, Manconi P, Becciu A, Tullio V, Palomba M, Auzzas L, Cerri R   +8 more
core   +2 more sources

Enhancement and Mechanism of Ergosterol Biosynthesis in Termite Ball Fungus Athelia termitophila by Methyl Jasmonate

Current Issues in Molecular Biology
Ergosterol is a component of fungal cell membranes that has physiological functions and applications in drugs, such as anti-inflammatory, anti-tumor, anti-fungal, and other immunosuppressive activities.
Yong-Gang Fang, Zahid Khan, Fang-Cheng Hu, Xiao-Hong Su, Lian-Xi Xing   +4 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Antimicrobial Evaluation of Sulfonamides after Coupling with Thienopyrimidine Coplanar Structure

Pharmaceuticals
This work describes the design and synthesis of three series of hybrids of thienopyrimidines and sulfonamides. Dihydrofolate reductase enzyme was selected as a target for the in-silico screening of the synthesized thienopyrimidine–sulfonamide hybrid as ...
Elshaymaa I. Elmongy, Wejdan S. Alanazi, Alhanouf I. Aldawsari, Asma A. Alfaouri, Reem Binsuwaidan   +4 more
doaj   +1 more source

Key Enzymes of Triterpenoid Saponin Biosynthesis and the Induction of Their Activities and Gene Expressions in Plants

Natural Product Communications, 2010
Triterpenoid saponins are one of the key active components of many medicinal plants. The biosynthetic pathway of triterpenoid saponins in higher plants and a lot of experimental results both indicated that the key enzymes involved in triterpenoid saponin
Chang Ling Zhao, Xiu Ming Cui, Yan Ping Chen, Quan Liang   +3 more
doaj   +1 more source

SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer

Frontiers in Immunology
BackgroundSqualene epoxidase (SQLE) is a key enzyme in cholesterol biosynthesis and has been shown to negatively affect tumor immunity and is associated with poor outcomes of immunotherapy in various cancers.
Junchen Pan, Haixi Liang, Lin Zhou, Wenhua Lu, Bitao Huo, Bitao Huo, Rui Liu, Peng Huang, Peng Huang   +8 more
doaj   +1 more source

Identification of the Arabidopsis dry2/sqe1-5 mutant reveals a central role for sterols in drought tolerance and regulation of reactive oxygen species.

, 2009
Squalene epoxidase enzymes catalyse the conversion of squalene into 2,3-oxidosqualene, the precursor of cyclic triterpenoids. Here we report that the Arabidopsis drought hypersensitive/squalene epoxidase 1-5 (dry2/sqe1-5) mutant, identified by its ...
Albert Ferrer, Itziar Castanedo, Ludivine Taconnat, Miguel A. Botella, Benjamín Nieto, Victoriano Valpuesta, Liam Dolan, David Posé, Abel Rosado, Omar Borsani   +9 more
core   +1 more source

Genetic and biochemical characterization of the squalene epoxidase gene family in Arabidopsis thaliana

, 2007
As sessile organisms, plants have developed the ability to synthesize an impressive array of metabolites to meet environmental challenges. Terpenes constitute the largest group of plant natural products, yet the biological functions of most of these ...
Rasbery, Jeanne M.
core