BioMed Research International, Volume 2020, Issue 1, 2020., 2020 Enzalutamide (ENZ) has been approved for the treatment of advanced prostate cancer (PCa), but some patients develop ENZ resistance initially or after long‐term administration. Although a few key genes have been discovered by previous efforts, the complete mechanisms of ENZ resistance remain unsolved.
Long Zheng +5 more
wiley +1 more source
Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow [PDF]
, 2015 Mastitis is a costly disease which hampers the dairy industry. Inflammation of the mammary gland is commonly caused by bacterial infection, mainly Escherichia coli, Streptococcus uberis and Staphylococcus aureus.
Chen, X +4 more
core +3 more sources
Mouse Stbd1 is N-myristoylated and affects ER–mitochondria association and mitochondrial morphology [PDF]
, 2021 Starch binding domain-containing protein 1 (Stbd1) is a carbohydrate-binding protein that has been proposed to be a selective autophagy receptor for glycogen.
Baba, Otto +7 more
core
Transcriptome profiling of granulosa cells of bovine ovarian follicles during growth from small to large antral sizes [PDF]
, 2014 Background: At later stages of folliculogenesis, the mammalian ovarian follicle contains layers of epithelial granulosa cells surrounding an antral cavity.
Harland, M. +5 more
core +2 more sources
AlphaFold2 SLiM screen for LC3-LIR interactions in autophagy. [PDF]
AutophagyIn selective macroautophagy/autophagy, cargo recruitment is mediated by MAP1LC3/LC3-interacting regions (LIRs)/Atg8-family interacting motifs (AIMs) in the cargo or cargo receptor proteins.
Stuke JFM, Hummer G.
europepmc +3 more sources
Effects of internal low-dose irradiation from 131I on gene expression in normal tissues in Balb/c mice [PDF]
, 2011 Background The aim of this study was to investigate the global gene expression response of normal tissues following internal low absorbed dose irradiation of 131I.
Emil Schüler +4 more
core +1 more source
Defective liver glycogen autophagy related to hyperinsulinemia in intrauterine growth-restricted newborn wistar rats [PDF]
, 2020 Maternal malnutrition plays a critical role in the developmental programming of later metabolic diseases susceptibility in the offspring, such as obesity and type 2 diabetes.
de Toro-Martín, Juan +6 more
core +1 more source
Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans [PDF]
, 2021 Objective: glycogen metabolism has emerged as a mediator in the control of energy homeostasis and studies in murine models reveal that adipose tissue might contain glycogen stores.
Ceperuelo-Mallafré, Victoria +17 more
core +1 more source
The Subgingival Host–Microbial Landscape in Mothers With Periodontitis and Their At‐Risk Offspring
Journal of Clinical Periodontology, Volume 53, Issue 2, Page 201-213, February 2026.ABSTRACT Aim To evaluate the subgingival proteome and microbiome of mothers with periodontitis and their offspring, thereby assessing signatures of periodontal diseases. Methods Forty participants in four groups were included: mothers with periodontitis and their offspring, as well as periodontally healthy mothers and their offspring.
Hélvis E. S. Paz +8 more
wiley +1 more source
British Journal of Pharmacology, Volume 182, Issue 19, Page 4625-4646, October 2025.Background and Purpose Most older people use polypharmacy (≥5 medications), particularly those with cardiovascular disease. The effects of polypharmacy on the cardiovascular system are not well described. We examined the effect of a chronic polypharmacy regimen on left ventricular (LV) function, structure and proteome in young and old mice of both ...
Trang Tran +9 more
wiley +1 more source