Liver glycogen metabolism is unchanged in mdx mice.
Means (± SEM) for glycogen synthase (A), glycogen branching enzyme (B), glycogen phosphorylase (C) activity, glycogen debranching enzyme protein expression (D), STBD1 protein expression (E) and PKA activity (F); n = 8.
Jennifer Trieu (535281) +8 more
core +1 more source
Myocardial glycophagy - A specific glycogen handling response to metabolic stress is accentuated in the female heart [PDF]
Cardiac metabolic stress is a hallmark of many cardiac pathologies, including diabetes. Cardiac glycogen mis-handling is a frequent manifestation of various cardiopathologies.
Delbridge, LMD +4 more
core +2 more sources
Abstract Background Transmembrane 4 L six family member 5 (TM4SF5) translocates subcellularly and functions metabolically, although it is unclear how intracellular TM4SF5 translocation is linked to metabolic contexts. It is thus of interests to understand how the traffic dynamics of TM4SF5 to subcellular endosomal membranes are correlated to regulatory
Ji Eon Kim +18 more
wiley +1 more source
Establishing the role of rare coding variants in known Parkinson's disease risk loci [PDF]
Many common genetic factors have been identified to contribute to Parkinson's disease (PD) susceptibility, improving our understanding of the related underlying biological mechanisms.
Heutink, P +17 more
core +3 more sources
Altered glycogen metabolism contributes to the increased muscle glycogen concentration in mdx mice.
Means (± SEM) for glycogen phosphorylase (A) and PKA activity (B) in skeletal muscles from BL10 wild type and mdx. n = 8; **P = 0.01 compared with skeletal muscle from BL/10 wild type mice.
Jennifer Trieu (535281) +8 more
core +1 more source
The palatability of beef, i.e., tenderness, juiciness, chewiness, and flavour, is an essential predictor of the eating experience of beef consumers. As the leading factor influencing palatability, beef tenderness can vary considerably even for the same ...
Zhu, Yao
core
Regulation and role of glycophagy in skeletal muscle energy metabolism
Glycophagy is the autophagic degradation of glycogen via the lysosomal enzyme GAA/alpha-acid glucosidase. Glycophagy is considered a housekeeping process to degrade poorly branched glycogen particles, but the regulation and role of glycophagy in skeletal
Timothy D. Heden (3710056) +3 more
core +1 more source
Exploring therapeutic targets for glycogen storage disease type 1 by modulating signal transduction pathways in hepatic in vivo and ex vivo models [PDF]
This PhD thesis investigates the regulation of glucose 6-phosphatase (G6PC)-independent glucose production in hepatic Glycogen Storage Disease (GSD) types Ia and Ib, aiming to optimize glucose homeostasis and reduce hepatic glycogen accumulation ...
Alagere Krishnamurthy, Kishore; id_orcid
core +1 more source
Loss of autophagy in chondrocytes causes severe growth retardation
Chondrogenesis is accompanied by not only cellular renovation, but also metabolic stress. Therefore, macroautophagy/autophagy is postulated to be involved in this process.
Satoshi Waguri (2179754) +5 more
core +1 more source
Investigation of the role of the glucose-6-phosphate translocase in the activation of autophagy and glycogen-selective autophagy in glycogen storage disease type IB patients [PDF]
Introduction: Glycogen storage disease type Ib (GSD-Ib) is characterized by a deficiency of glucose-6- phosphate translocase (G6PT) encoded by the SLC37A4 gene, affecting glucose homeostasis and disrupting autophagy.
Jocić, Nikola +11 more
core

