Results 41 to 50 of about 1,282 (170)

From biofilm disinfection to bacterial stem cell modulation and dentin matrix-driven stem cell mineralization [PDF]

open access: yes, 2020
Caries or trauma are common occurrences in the permanent dentition of young patients. They often result in pulp necrosis, root canal infection, inflammation (apical periodontitis) and arrest of further root development.
Petridis, Xenos
core   +1 more source

Recent Advances in Apical Periodontitis Treatment: A Narrative Review [PDF]

open access: yes, 2023
Apical periodontitis is an inflammatory response caused by pulp infection. It induces bone resorption in the apical and periapical regions of the tooth. The most conservative approach to treat this condition is nonsurgical endodontic treatment.
Arias, Zulema   +7 more
core   +1 more source

Epigallocatechin-3-Gallate Promotes Osteo-/Odontogenic Differentiation of Stem Cells from the Apical Papilla through Activating the BMP–Smad Signaling Pathway

open access: yesMolecules, 2021
Stem cells from apical papilla (SCAPs) are desirable sources of dentin regeneration. Epigallocatechin-3-gallate (EGCG), a natural component of green tea, shows potential in promoting the osteogenic differentiation of bone mesenchymal stem cells. However,
Zeni Liu   +4 more
doaj   +1 more source

Circular RNA SIPA1L1 regulates osteoblastic differentiation of stem cells from apical papilla via miR-204-5p/ALPL pathway

open access: yesStem Cell Research & Therapy, 2020
Background Osteogenesis is a complex biological process which requires the coordination of multiple molecular mechanisms. This research aimed to explore the biological role and underlying regulatory mechanism of circSIPA1L1 during the osteogenic ...
Yuzhi Li   +6 more
doaj   +1 more source

Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study

open access: yesBiological Procedures Online, 2023
Background Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global therapeutic challenges. The differentiation of human stem cells from apical papilla into cementoblasts may provide a strategy
Morvarid Ebadi   +4 more
doaj   +1 more source

A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla

open access: yesJournal of Dental Sciences, 2022
Background/purpose: CD24 is a specific cell surface marker for undifferentiated dental stem cells from apical papilla (SCAPs) seen only during root development, before the tooth emerges through gum.
Jing Liang   +5 more
doaj   +1 more source

Cyclic Adenosine Monophosphate Promotes Odonto/Osteogenic Differentiation of Stem Cells from the Apical Papilla via Suppression of Transforming Growth Factor Beta 1 Signaling [PDF]

open access: yes, 2019
Introduction: Stem cells from the apical papilla (SCAPs) possess strong odonto/osteogenic differentiation potential. This study investigated the effect of cyclic adenosine monophosphate (cAMP) on odonto/osteogenic differentiation of SCAPs and the ...
Chu, CH, Quan, LL, Zhang, C, Zhang, J
core   +1 more source

Isolation and Culture of Human Stem Cells from Apical Papilla under Low Oxygen Concentration Highlight Original Properties

open access: yesCells, 2019
: Stem cells isolated from the apical papilla of wisdom teeth (SCAPs) are an attractive model for tissue repair due to their availability, high proliferation rate and potential to differentiate in vitro towards mesodermal and neurogenic lineages.
Murielle Rémy   +8 more
doaj   +1 more source

MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1

open access: yesInternational Journal of Oral Science, 2023
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising treatment for spinal cord injury (SCI), but improving the neurogenic potential of MSCs remains a challenge.
Chen Zhang   +5 more
doaj   +1 more source

The Effect of Liquid-Phase Exfoliated Graphene Film on Neurodifferentiation of Stem Cells from Apical Papilla [PDF]

open access: yes, 2022
Background: Dental stem cells, which originate from the neural crest, due to their easy accessibility might be good candidates in neuro-regenerative procedures, along with graphene-based nanomaterials shown to promote neurogenesis in vitro.
Lazarević, M.   +7 more
core   +2 more sources

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