Results 131 to 140 of about 14,256 (222)

Visible‐Light Mediated Functionalization in Phe‐Containing Peptides Upon a Debenzylative Amination Process

Advanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
Selective late‐stage modification of N‐terminal phenylalanine short peptides is achived by visible‐light initiated reaction with N‐iodoimides in a debenzylation–amination process. This metal‐free method permits the incorporation of N‐containing heterocycles into the α‐position of the peptide backbone.
Guillermo Morales‐Ortega, Iván Pérez‐Cubero, Enrique Gómez‐Bengoa, Arkaitz Correa, Javier Carreras   +4 more
wiley   +1 more source

A theoretical study on the feasibility of 1,4-Copper migration in the Cu-catalyzed formal hydro(borylmethylsilyl)ation of internal alkynes. [PDF]

Commun Chem
Liu S, Chen W, Long X, Zhang D, Chen J, Zhu Z, Wei H.   +6 more
europepmc   +1 more source

Synthesis of Niraparib via Chemoenzymatic Dearomatization of Substituted Pyridines

Advanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
The synthesis of the PARP inhibitor Niraparib has been achieved via a chemoenzymatic dearomatization strategy. Chemical reduction combined with a one‐pot enzymatic cascade comprising an amine oxidase (AmOx) and an ene imine reductase (EneIRED) allowed for asymmetric reduction with high enantioselectivity.
Tabea Gerlach, Lucian Pirvu, Sam Butterworth, Nicholas J. Turner   +3 more
wiley   +1 more source

Stereoselective additions to alkenylphosphonium salts for the synthesis of P-stereogenic compounds. [PDF]

Chem Sci
Chen XB, Padín D, Feringa BL.
europepmc   +1 more source

Electro‐Mediated Redox Functionalization of Conjugated 1,3‐Dienes

Advanced Synthesis &Catalysis, Volume 368, Issue 6, 17 March 2026.
This review aims at providing a comprehensive view of the emerging field of electro‐mediated functionalization of conjugated 1,3‐dienes, highlighting key developments, mechanistic insights, and remaining challenges. It highlights the efficient use of electron as the sole reagent to access highly substituted allylic compounds from simple and readily ...
Ophélie Montiège, Jean‐François Brière, Cédric Schneider, Hélène Beucher   +3 more
wiley   +1 more source

Palladium-Catalyzed Regio- and Stereoselective C-H Alkynylation of Conjugated Dienols. [PDF]

JACS Au
Yang MW, Lu HX, Zhang JW, Xu YH.
europepmc   +1 more source

Regio- and stereoselectivity of polar [2+3] cycloaddition reactions between (Z)-C-(3,4,5-trimethoxyphenyl)-N-methylnitrone and selected (E)-2-substituted nitroethenes

Open Chemistry, 2014
Jasiński Radomir, Ziółkowska Magda, Demchuk Oleh, Maziarka Agata   +3 more
doaj   +1 more source

Computational Analysis of the Asymmetric Hydrogenation of γ-Ketoacids: Weak Interactions and Kinetics. [PDF]

Molecules
Golovanov IS, Pospelov EV.
europepmc   +1 more source

Iron-Catalyzed Tunable Double Bond Migration and Geometrical Isomerization in Olefins via a Spin-Accelerated Alkyl Mechanism. [PDF]

Angew Chem Int Ed Engl
Obeid AH, Herrero C, Guillot R, Hannedouche J.   +3 more
europepmc   +1 more source

Photoredox-controlled chemo-divergent, regio-, and stereoselective difunctionalization of olefins via switchable SO₂ reintegration. [PDF]

Sci Adv
Xia J, Zhu L, Lv Z, Guo Y, Lin L, Sun J, Zheng G, Zhang Q.   +7 more
europepmc   +1 more source