Results 251 to 260 of about 32,791,583 (267)
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Chemico-Biological Interactions, 2018
Previously we have demonstrated that stromal interacting molecule-1 (STIM1) was involved in ethanol induced liver injury. However, the exact pathogenic mechanism of STIM1 in alcoholic liver disease (ALD) is still unknown. We constructed plasmid vectors encoding short-hairpin RNA against STIM1 to investigate its role in ALD in the rat liver cell line ...
Ruibing, Cui +4 more
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Previously we have demonstrated that stromal interacting molecule-1 (STIM1) was involved in ethanol induced liver injury. However, the exact pathogenic mechanism of STIM1 in alcoholic liver disease (ALD) is still unknown. We constructed plasmid vectors encoding short-hairpin RNA against STIM1 to investigate its role in ALD in the rat liver cell line ...
Ruibing, Cui +4 more
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Structural and Functional Investigations of Stromal Interaction Molecule 1
2022Calcium (Ca2+) ist ein wichtiger zellulärer Botenstoff, der an biologischen Signalprozessen, die für Befruchtung, Genexpression, Zellwachstum und Zelldifferenzierung, Immunabwehr, Muskelkontraktion sowie Apoptose erforderlich sind, beteiligt ist. Aufgrund seiner Bedeutung ist es für Zellen unerlässlich, das intrazelluläre Ca2+ streng zu regulieren, was
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Hypertension Research, 2018
In vascular endothelial cells, store-operated calcium entry (SOCE) activates endothelial NO synthase (eNOS) and regulates nitric oxide (NO) production as well as flow-dependent mechanical stimuli. Stromal interaction molecule 1, or STIM1, was recently identified to be essential for SOCE, acting as a calcium sensor for intracellular calcium stores ...
Mitsuhiro, Nishimoto +3 more
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In vascular endothelial cells, store-operated calcium entry (SOCE) activates endothelial NO synthase (eNOS) and regulates nitric oxide (NO) production as well as flow-dependent mechanical stimuli. Stromal interaction molecule 1, or STIM1, was recently identified to be essential for SOCE, acting as a calcium sensor for intracellular calcium stores ...
Mitsuhiro, Nishimoto +3 more
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Stromal Interaction Molecule 1 Disruption Protects Myocardial from Ischemia ‐ Reperfusion Injury
The FASEB Journal, 2016Background It has been reported that the increase in Stromal Interacting Molecule 1 (STIM1) expression is associated with myocardial complication. However, the role of vascular STIM1 in cardiac ischemia‐reperfusion (I/R) injury is unknown.
Vishal R Mali +5 more
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[Impact of stromal interaction molecule 1 silencing on cell cycle of endothelial progenitor cells].
Zhonghua xin xue guan bing za zhi, 2012To investigate the effect of stromal interaction molecule 1 (STIM1) silencing on EPCs cell cycle.Rat bone marrow derived endothelial progenitor cells (EPCs) were isolated and cultured in L-DMEM with 20% FBS. Ad-si/rSTIM1 and Ad-hSTIM1 were then transfected into EPCs and the expression of STIM1 mRNA was detected by RT-PCR.
Chun-Yan, Kuang +5 more
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[Stromal interaction molecule 1 and cardiovascular diseases].
Zhonghua xin xue guan bing za zhi, 2012Chun-Yan, Kuang, Lan, Huang
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