Results 71 to 80 of about 95,299 (308)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Subcellular localization of retinoids, retinoid-binding proteins, and acyl-CoA:retinol acyltransferase in rat liver

Journal of Lipid Research, 1987
Studies were conducted to define the subcellular localization of endogenous retinoids (vitamin A), retinoid-binding proteins, and acyl-CoA:retinol acyltransferase (ARAT) in liver and to determine whether their distributions were affected by hepatic ...
E H Harrison, W S Blaner, D S Goodman, A C Ross   +3 more
doaj   +1 more source

Protein-Turnover in Subcellular-Fractions of Brain From the Ethanol-Fed Rat

, 1987
The effect of ethanol consumption (27% of energy intake) for 21 days, on protein synthesis and degradation in subcellular fractions of rat brain was investigated using the Na CO labelling procedure. Ethanol administration elicited an increase in the rate
Mason, S, Tiernan, JM, Ward, LC, Hayling, N   +3 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Legumain, cystatin E/M and cathepsin L expressions in subcellular fractions of HCT116 and SW620 cells.

, 2013
(A) Immunoblots of legumain in lysosomal (L) and nuclear (N) fractions enriched from HCT116 and SW620 cells using density gradient centrifugation. All lanes were loaded with 15 µg total protein from each fraction.
Kjersti Flatmark (76807), Solveig J. Pettersen (103826), Harald T. Johansen (103823), Rigmor Solberg (103828), Klaudia Brix (83269), Mads H. Haugen (103820), Gunhild M. Maelandsmo (103830)   +6 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Subcellular Partitioning of Trace Elements Is Related to Metal Ecotoxicological Classes in Livers of Fish (Esox lucius; Coregonus clupeaformis) from the Yellowknife Area (Northwest Territories, Canada)

Toxics
The subcellular partitioning of trace elements (TEs) may depend on their binding preferences, although few field data are available from mining-impacted areas.
Aymeric Rolland, Mike Palmer, John Chételat, Marc Amyot, Maikel Rosabal   +4 more
doaj   +1 more source

Effects of alpha-linolenic acid vs. docosahexaenoic acid supply on the distribution of fatty acids among the rat cardiac subcellular membranes after a short- or long-term dietary exposure

Nutrition & Metabolism, 2009
Background Previous work showed that the functional cardiac effect of dietary alpha-linolenic acid (ALA) in rats requires a long feeding period (6 months), although a docosahexaenoic (DHA) acid-supply affects cardiac adrenergic response after 2 months ...
Rousseau-Ralliard Delphine, Weill Pierre, Grynberg Alain, Macaire Jean-Paul, Auchere Daniel, Guinot Marine, Brochot Amandine   +6 more
doaj   +1 more source

Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions

, 2016
The liver plays an important role in metabolism and elimination of xenobiotics, including drugs. Determination of concentrations of proteins involved in uptake, distribution, metabolism, and excretion of xenobiotics is required to understand and predict ...
Wisniewski, Jacek R.,, Wegler, Christine,, Artursson, Per, Wisniewski, J., Wegler, Christine, Artursson, Per,, Artursson, P., Wegler, C., Wisniewski, Jacek R.   +8 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source