Results 11 to 20 of about 7,622 (205)

Ultrasonic-boosted succinylation of walnut protein isolate: Unlocking enhanced functionalities and structural insights [PDF]

Food Chemistry: X
This study aims to improve the functional properties of walnut protein isolate (WPI), particularly its solubility and interfacial activity, through ultrasound-assisted succinylation. WPI was treated with succinic anhydride at concentrations of 5 %, 10 %,
Weizhuo Zhu, Liping Sun, Ying Gu, Yongliang Zhuang, Gaopeng Zhang, Xuejing Fan, Yangyue Ding   +6 more
doaj   +2 more sources

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Lysine succinylation, the metabolic bridge between cancer and immunity

Genes and Diseases, 2023
Lysine succinylation is a naturally occurring post-translational modification (PTM) that regulates the stability and function of proteins. It can be regulated by enzymes such as SIRT5 and SIRT7.
Rui Shen, Hongyun Ruan, Shuye Lin, Bin Liu, Hang Song, Lu Li, Teng Ma   +6 more
doaj   +1 more source

GPSuc: Global Prediction of Generic and Species-specific Succinylation Sites by aggregating multiple sequence features. [PDF]

PLoS ONE, 2018
Lysine succinylation is one of the dominant post-translational modification of the protein that contributes to many biological processes including cell cycle, growth and signal transduction pathways.
Md Mehedi Hasan, Hiroyuki Kurata
doaj   +1 more source

iSuc-ChiDT: a computational method for identifying succinylation sites using statistical difference table encoding and the chi-square decision table classifier

BioData Mining, 2022
Background Lysine succinylation is a type of protein post-translational modification which is widely involved in cell differentiation, cell metabolism and other important physiological activities.
Ying Zeng, Yuan Chen, Zheming Yuan
doaj   +1 more source

Proteome-Wide Identification of Lysine Succinylation in the Proteins of Tomato (Solanum lycopersicum). [PDF]

PLoS ONE, 2016
Post-translational modification of proteins through lysine succinylation plays important regulatory roles in living cells. Lysine succinylation was recently identified as a novel post-translational modification in Escherichia coli, yeast, Toxoplasma ...
Weibo Jin, Fangli Wu
doaj   +1 more source

Succinylation Regulators Promote Clear Cell Renal Cell Carcinoma by Immune Regulation and RNA N6-Methyladenosine Methylation

Frontiers in Cell and Developmental Biology, 2021
Succinylation is a newly discovered and multienzyme-regulated post-translational modification (PTM) that is associated with the initiation and progression of cancer. Currently, no systematic analyses on the role of succinylation regulators in tumors have
Wenqing Lu, Wenqing Lu, Wenqing Lu, Xiaofang Che, Xiaofang Che, Xiaofang Che, Xiujuan Qu, Xiujuan Qu, Xiujuan Qu, Chunlei Zheng, Chunlei Zheng, Chunlei Zheng, Xianghong Yang, Bowen Bao, Bowen Bao, Bowen Bao, Zhi Li, Zhi Li, Zhi Li, Duo Wang, Duo Wang, Duo Wang, Yue Jin, Yue Jin, Yue Jin, Yizhe Wang, Jiawen Xiao, Jianfei Qi, Yunpeng Liu, Yunpeng Liu, Yunpeng Liu   +30 more
doaj   +1 more source

Succinylation Improves the Thermal Stability of Egg White Proteins

Molecules, 2019
Succinylation can improve the thermal stability of various proteins. In this study, succinylated egg white protein (SEWP) samples with different succinylation degrees were prepared by adding various succinic anhydride additives to egg white protein (EWP).
Dabo He, Ying Lv, Qigen Tong
doaj   +1 more source

Lysine Succinylation Is a Frequently Occurring Modification in Prokaryotes and Eukaryotes and Extensively Overlaps with Acetylation

Cell Reports, 2013
Recent studies have shown that lysines can be posttranslationally modified by various types of acylations. However, except for acetylation, very little is known about their scope and cellular distribution.
Brian T. Weinert, Christian Schölz, Sebastian A. Wagner, Vytautas Iesmantavicius, Dan Su, Jeremy A. Daniel, Chunaram Choudhary   +6 more
doaj   +1 more source

HDAC1/2/3 are major histone desuccinylases critical for promoter desuccinylation

Cell Discovery, 2023
Lysine succinylation is one of the major post-translational modifications occurring on histones and is believed to have significant roles in regulating chromatin structure and function.
Jialun Li, Lu Lu, Lingling Liu, Xuelian Ren, Jiwei Chen, Xingzhi Yin, Yanhui Xiao, Jiwen Li, Gang Wei, He Huang, Wei Wei, Jiemin Wong   +11 more
doaj   +1 more source