Results 21 to 30 of about 7,622 (205)

Succinylated Octopamine Ascarosides and a New Pathway of Biogenic Amine Metabolism in Caenorhabditis elegans [PDF]

, 2013
The ascarosides, small-molecule signals derived from combinatorial assembly of primary metabolism-derived building blocks, play a central role in Caenorhabditis elegans biology and regulate many aspects of development and behavior in this model ...
Artyukhin, Alexander B., Avery, Leon, Baugh, L. Ryan, Bose, Neelanjan, Cheong, Micheong, Izrayelit, Yevgeniy, Jo, Yeara, Jordan, James M., Schroeder, Frank C., Srinivasan, Jagan, Sternberg, Paul W., von Reuss, Stephan H., Yim, Joshua J.   +12 more
core   +2 more sources

Cyclic β-glucans at the bacteria–host cells interphase: One sugar ring to rule them all [PDF]

, 2018
Cyclic β‐1,2‐D‐glucans (CβG) are natural bionanopolymers present in the periplasmic space of many Proteobacteria. These molecules are sugar rings made of 17 to 25 D‐glucose units linked exclusively by β‐1,2‐glycosidic bonds.
Arce Gorvel, Vilma, Ciocchini, Andres Eduardo, Comerci, Diego José, Gorvel, Jean-Pierre, Guidolin, Leticia Soledad   +4 more
core   +1 more source

DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction

BMC Bioinformatics, 2020
Background Protein succinylation has recently emerged as an important and common post-translation modification (PTM) that occurs on lysine residues. Succinylation is notable both in its size (e.g., at 100 Da, it is one of the larger chemical PTMs) and in
Niraj Thapa, Meenal Chaudhari, Sean McManus, Kaushik Roy, Robert H. Newman, Hiroto Saigo, Dukka B. KC   +6 more
doaj   +1 more source

Success: evolutionary and structural properties of amino acids prove effective for succinylation site prediction [PDF]

, 2018
Post-translational modification is considered an important biological mechanism with critical impact on the diversification of the proteome. Although a long list of such modifications has been studied, succinylation of lysine residues has recently ...
Dehzangi, Abdollah, Lal, Sunil P., López, Y., Sattar, A., Sharma, Alokanand, Taherzadeh, G., Tsunoda, T.   +6 more
core   +1 more source

Exclusive neuronal expression of SUCLA2 in the human brain [PDF]

, 2013
SUCLA2 encodes the ATP-forming subunit (A-SUCL-) of succinyl-CoA ligase, an enzyme of the citric acid cycle. Mutations in SUCLA2 lead to a mitochondrial disorder manifesting as encephalomyopathy with dystonia, deafness and lesions in the basal ganglia ...
A Kowluru, A Minelli, A Navarro-Sastre, A Rotig, A Vozza, AA Gerencser, AC Yu, Aniko Gál, Arpád Dobolyi, Attila G. Bagó, B Przybyla-Zawislak, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Chinopoulos, C Miller, Christos Chinopoulos, DO Lambeth, E Brekke, E Ostergaard, E Ostergaard, E Ostergaard, E Ostergaard, E Pfaff, EE McKee, EE McKee, EF Kadrmas, Elsebet Ostergaard, F Conti, F Conti, G Kiss, JC Wallace, JD Johnson, JH Ottaway, L Milon, M Lopes-Cardozo, M Palkovits, M Thomson, Miklós Palkovits, ML Pall, Mária J. Molnár, N Westergaard, O Elpeleg, R Carrozzo, R Dringen, RF Labbe, RL Strausberg, RP Shank, S Tanner, Tamás Dóczi, TM Jenkins, U Sonnewald, Vera Adam-Vizi, X Li, Z Zhang   +55 more
core   +2 more sources

Succinylation of Pepsinogen

Journal of Biological Chemistry, 1967
Succinic anhydride reacts with pepsinogen to form succinylpepsinogen in which the 10 e-amino groups of the lysine residues are succinylated. In addition reaction occurs with 16 tyrosine residues and 10 to 13 hydroxyamino acid residues of the protein. In contrast to the O-succinyltyrosines of succinylpepsinogen which are spontaneously decomposed in 3 to
A D, Gounaris, G E, Perlmann
openaire   +2 more sources

Succinylated lysine residue prediction revisited

Briefings in Bioinformatics, 2022
AbstractMotivationLysine succinylation is a kind of post-translational modification (PTM) which plays a crucial role in regulating the cellular processes. Aberrant succinylation may cause inflammation, cancers, metabolism diseases and nervous system diseases. The experimental methods to detect succinylation sites are time-consuming and costly.
Shehab Sarar Ahmed, Zaara Tasnim Rifat, Mohammad Saifur Rahman, M. Sohel Rahman   +3 more
openaire   +2 more sources

Global analysis of protein lysine succinylation profiles in common wheat

BMC Genomics, 2017
Background Protein lysine succinylation is an important post-translational modification and plays a critical regulatory role in almost every aspects of cell metabolism in both eukaryotes and prokaryotes.
Yumei Zhang, Guangyuan Wang, Limin Song, Ping Mu, Shu Wang, Wenxing Liang, Qi Lin   +6 more
doaj   +1 more source

Effects of increasing acylation and enzymatic hydrolysis on functional properties of bambara bean (Vigna subterranea) protein concentrate [PDF]

, 2013
Bambara bean protein concentrate was acylated and partially hydrolysed with pancreatin in order to improve its functional properties. Increasing acetylation and succinylation (from 0.0 to 1.0 g anhydride/g concentrate) modified lysine at similar rate ...
Mbome, I., Minka, S., Mune Mune, M.
core   +1 more source

Succinyl Phosphate and the Succinyl Coenzyme A Synthetase Reaction

Journal of Biological Chemistry, 1969
Trilithium succinyl phosphate of a high degree of purity has been synthesized chemically. It is active in the synthesis of ATP from ADP in a reaction catalyzed by succinyl coenzyme A synthetase from Escherichia coli (succinate: CoA ligase (ADP); EC 6.2.1.5).
J G, Hildebrand, L B, Spector
openaire   +2 more sources