Results 1 to 10 of about 519 (109)

Global proteome analyses of phosphorylation and succinylation of barley root proteins in response to phosphate starvation and recovery [PDF]

Frontiers in Plant Science, 2022
Phosphate (Pi) stress is an important environmental factor that limits plant growth and development. Of various posttranslational modifications (PTMs), protein phosphorylation and succinylation are the two most important PTMs that regulate multiple ...
Juncheng Wang, Juncheng Wang, Chengdao Li, Lirong Yao, Lirong Yao, Zengke Ma, Zengke Ma, Panrong Ren, Panrong Ren, Erjing Si, Erjing Si, Baochun Li, Yaxiong Meng, Yaxiong Meng, Xiaole Ma, Xiaole Ma, Ke Yang, Ke Yang, Xunwu Shang, Huajun Wang, Huajun Wang   +20 more
doaj   +5 more sources

First Succinylome Profiling of Vibrio alginolyticus Reveals Key Role of Lysine Succinylation in Cellular Metabolism and Virulence [PDF]

Frontiers in Cellular and Infection Microbiology, 2021
Recent studies have shown that a key strategy of many pathogens is to use post-translational modification (PTMs) to modulate host factors critical for infection.
Fuyuan Zeng, Fuyuan Zeng, Fuyuan Zeng, Huanying Pang, Huanying Pang, Huanying Pang, Huanying Pang, Ying Chen, Ying Chen, Hongwei Zheng, Hongwei Zheng, Wanxin Li, Srinivasan Ramanathan, Rowena Hoare, Sean J. Monaghan, Xiangmin Lin, Jichang Jian, Jichang Jian, Jichang Jian, Jichang Jian   +19 more
doaj   +6 more sources

Acetylome and Succinylome Profiling of Edwardsiella tarda Reveals Key Roles of Both Lysine Acylations in Bacterial Antibiotic Resistance [PDF]

Antibiotics, 2022
The antibiotic resistance of Edwardsiella tarda is becoming increasingly prevalent, and thus novel antimicrobial strategies are being sought. Lysine acylation has been demonstrated to play an important role in bacterial physiological functions, while its
Yuying Fu, Lishan Zhang, Huanhuan Song, Junyan Liao, Li Lin, Wenjia Jiang, Xiaoyun Wu, Guibin Wang   +7 more
doaj   +2 more sources

Identification of Lysine Succinylome and Acetylome in the Vancomycin-Intermediate Staphylococcus aureus XN108 [PDF]

Microbiology Spectrum, 2022
Protein posttranslational modifications (PTMs) play important roles in regulating numerous biological functions of prokaryotic and eukaryotic organisms.
Li Tan, Yi Yang, Weilong Shang, Zhen Hu, Huagang Peng, Shu Li, Xiaomei Hu, Xiancai Rao   +7 more
doaj   +2 more sources

Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant Staphylococcus aureus (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics [PDF]

mBio, 2021
mecAsucC
Christopher Campbell, Claire Fingleton, Merve S. Zeden, Emilio Bueno, Laura A. Gallagher, Dhananjay Shinde, Jongsam Ahn, Heather M. Olson, Thomas L. Fillmore, Joshua N. Adkins, Fareha Razvi, Kenneth W. Bayles, Paul D. Fey, Vinai C. Thomas, Felipe Cava, Geremy C. Clair, James P. O’Gara   +16 more
doaj   +3 more sources

Dynamic Responses of Barley Root Succinyl-Proteome to Short-Term Phosphate Starvation and Recovery [PDF]

Frontiers in Plant Science, 2021
Barley (Hordeum vulgare L.)—a major cereal crop—has low Pi demand, which is a distinct advantage for studying the tolerance mechanisms of phosphorus deficiency.
Juncheng Wang, Juncheng Wang, Zengke Ma, Zengke Ma, Chengdao Li, Panrong Ren, Panrong Ren, Lirong Yao, Lirong Yao, Baochun Li, Yaxiong Meng, Yaxiong Meng, Xiaole Ma, Xiaole Ma, Erjing Si, Erjing Si, Ke Yang, Ke Yang, Xunwu Shang, Huajun Wang, Huajun Wang   +20 more
doaj   +3 more sources

Comprehensive analysis of the succinylome in Vero cells infected with peste des petits ruminants virus Nigeria 75/1 vaccine strain [PDF]

BMC Veterinary Research
Background Peste des petits ruminants virus (PPRV) is currently the only member of the Morbillivirus caprinae species within the genus Morbillivirus of the family Paramyoxviridae.
Xuelian Meng, Xueliang Zhu, Xiangwei Wang, Rui Zhang, Zhidong Zhang, Yuefeng Sun   +5 more
doaj   +2 more sources

Comprehensive succinylome analyses reveal that hyperthermia upregulates lysine succinylation of annexin A2 by downregulating sirtuin7 in human keratinocytes. [PDF]

J Transl Int Med, 2023
Background and Objectives: Local hyperthermia at 44°C can clear multiple human papillomavirus (HPV)-infected skin lesions (warts) by targeting a single lesion, which is considered as a success of inducing antiviral immunity in the human body ...
Niu X, Zhao Y, Zhang T, Sun Y, Wei Z, Fu K, Li J, Tang M, Wan W, Gao X, Chen H, Qi R, Song B.   +12 more
europepmc   +3 more sources

Quantitative proteome and lysine succinylome characterization of zinc chloride smoke-induced lung injury in mice [PDF]

Heliyon
The inhalation of zinc chloride (ZnCl2) smoke is one of common resources of lung injury, potentially resulting in severe pulmonary complications and even mortality.
Rui Zhou, Zhiwei Tu, Daishi Chen, Wanmei Wang, Shuzi Liu, Linjun She, Zhan Li, Jihong Liu, Yabin Li, Yu Cui, Pan Pan, Fei Xie   +11 more
doaj   +2 more sources

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease. [PDF]

Nat Commun, 2022
Producción CientíficaAbnormalities in brain glucose metabolism and accumulation of abnormal protein deposits called plaques and tangles are neuropathological hallmarks of Alzheimer’s disease (AD), but their relationship to disease pathogenesis and to ...
Yang Y, Tapias V, Acosta D, Xu H, Chen H, Bhawal R, Anderson ET, Ivanova E, Lin H, Sagdullaev BT, Chen J, Klein WL, Viola KL, Gandy S, Haroutunian V, Beal MF, Eliezer D, Zhang S, Gibson GE.   +18 more
europepmc   +3 more sources