Results 131 to 140 of about 17,770 (172)
Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant. [PDF]
Glycoconj JHe P +13 more
europepmc +1 more source
Inhibition of sulfated glycans on the binding of dengue virus envelope protein to heparin. [PDF]
Glycoconj JYang J +8 more
europepmc +1 more source
Structure and Antiviral Activity of Sulfated Fucans From Stoechospermum marginatum [PDF]
Phytochemistry, 2006 A sulfated fucan containing fraction (SmWE) was isolated from water extract of the brown seaweed Stoechospermum marginatum collected from the Arabian Sea. Anion exchange chromatography of the crude fraction results in the production of a sulfated fucan (F3) having a molecular mass of 40 kDa and specific rotation [alpha]D(30) - 124 degrees (c 0.5, H2O).
Bimalendu Ray, Elsa B Damonte
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Molecular Characterization and Immunomodulatory Activity of Sulfated Fucans From Agarum cribrosum
Carbohydrate Polymers, 2014 The sulfated-fucans, known as fucoidans, were isolated from Agarum cribrosum and fractionated using ion-exchange chromatography to determine their molecular characteristics and in vitro immunomodulatory activity. The crude and fractionated fucoidans (F1 and F2) consisted mostly of carbohydrates (52.4-56.0%), sulfates (12.7-23.0%) and uronic acid (14.1 ...
Jin-Kyung Kim +2 more
exaly +4 more sources
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Carbohydrate Polymers, 2022
Sulfated fucans are important polysaccharides with diverse biological and biomedical activities. Carbohydrate-binding modules (CBMs) could serve as beneficial tools for the investigation of polysaccharides. Nevertheless, no sulfated fucan-binding CBM has been hitherto discovered.
Changhu Xue +2 more
exaly +3 more sources
Sulfated fucans are important polysaccharides with diverse biological and biomedical activities. Carbohydrate-binding modules (CBMs) could serve as beneficial tools for the investigation of polysaccharides. Nevertheless, no sulfated fucan-binding CBM has been hitherto discovered.
Changhu Xue +2 more
exaly +3 more sources
Sulfated Fucans, Fresh Perspectives: Structures, Functions, and Biological Properties of Sulfated Fucans and an Overview of Enzymes Active Toward This Class of Polysaccharide [PDF]
Glycobiology, 2003 Sulfated fucans, frequently referred to simply as fucans, constitute a class of polysaccharides first isolated in 1913. For many years fucans were regarded only as a potential source of l-fucose, although their anticoagulant activity was known. Even as the potent effects of fucans on physiological systems have become better characterized, structural ...
Olivier Berteau
exaly +3 more sources
Use of Sulfated Fucans as Anticoagulant and Antithrombotic Agents: Future Perspectives
Current Pharmaceutical Design, 2004Sulfated alpha-L-fucans from brown algae (also known as fucoidan) have complex and heterogeneous structures but recent studies revealed the occurrence of ordered repeat units in the sulfated fucans from several species. Even in these cases, the presence of highly branched portions and the complex distributions of sulfate and acetyl groups highlight the
Paulo A.S. Mourão
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Role of Basic Amino Acids in the Interaction of Bindin With Sulfated Fucans
Biochemistry, 1988Bindin, the acrosomal sperm adhesion protein of the sea urchin Strongylocentrotus purpuratus, binds specifically and with high affinity (Kd = 10(-8) M) to egg sulfated fucans in the high ionic strength milieu of seawater (0.55 M salt). Previous studies indicated that the negatively charged sulfate groups of the polysaccharide are critical for binding ...
Charles G. Glabe +2 more
exaly +3 more sources
A sulfated α-l-fucan from sea cucumber
Carbohydrate Research, 1994A purified sulfated alpha-L-fucan from the sea cucumber body wall was studied, before and after almost complete desulfation, using methylation analysis and NMR spectroscopy. NMR analysis indicates that 2,4-di-O-sulfo-L-fucopyranose and unsubstituted fucopyranose are present in equal proportions, and that 2-O-sulfo-L-fucopyranose is present in twice ...
A C, Ribeiro +3 more
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Relationship between Sulfate Groups and Biological Activities of Fucans
Thrombosis Research, 2000The anticoagulant and antiproliferative effects of low molecular weight fucans with different sulfate content were examined. The anticoagulant activity was determined by activated partial thromboplastin time and the antiproliferative one was achieved in vitro on CCL39 fibroblast cell line.
F, Haroun-Bouhedja +3 more
openaire +2 more sources