Results 151 to 160 of about 1,407 (187)
Sulfated fucans, fresh perspectives: structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide [PDF]
Glycobiology, 2003 Sulfated fucans, frequently referred to simply as fucans, constitute a class of polysaccharides first isolated in 1913. For many years fucans were regarded only as a potential source of l-fucose, although their anticoagulant activity was known. Even as the potent effects of fucans on physiological systems have become better characterized, structural ...
Olivier Berteau
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Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum
Phytochemistry, 2006 A sulfated fucan containing fraction (SmWE) was isolated from water extract of the brown seaweed Stoechospermum marginatum collected from the Arabian Sea. Anion exchange chromatography of the crude fraction results in the production of a sulfated fucan (F3) having a molecular mass of 40 kDa and specific rotation [alpha]D(30) - 124 degrees (c 0.5, H2O).
Bimalendu Ray
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Water soluble sulfated-fucans with immune-enhancing properties from Ecklonia cava
International Journal of Biological Macromolecules, 2014Water-soluble sulfated fucans isolated from Ecklonia cava were fractionated using an anion-exchange chromatography to investigate their molecular characteristics and immunomodulating activities. The crude fucoidan extract and purified fractions (EF1, EF2, and EF3) consisted mostly of different ratios of neutral sugars, proteins, sulfates, uronic acids,
SangGuan You
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Molecular characterization and immunomodulatory activity of sulfated fucans from Agarum cribrosum
Carbohydrate Polymers, 2014The sulfated-fucans, known as fucoidans, were isolated from Agarum cribrosum and fractionated using ion-exchange chromatography to determine their molecular characteristics and in vitro immunomodulatory activity. The crude and fractionated fucoidans (F1 and F2) consisted mostly of carbohydrates (52.4-56.0%), sulfates (12.7-23.0%) and uronic acid (14.1 ...
Dong-Jin Lee +2 more
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Sulfated fucans and a sulfated galactan from sea urchins as potent inhibitors of selectin-dependent hematogenous metastasis [PDF]
Glycobiology, 2018 Metastasis is responsible for the majority of cancer-associated deaths, though only a very small number of tumor cells are able to efficiently complete all the steps of that process. Tumor cell survival in the bloodstream is one of the limiting aspects of the metastatic cascade.
Lubor Borsig +1 more
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Sulfated fucans extracted from algae Padina gymnospora have anti-inflammatory effect [PDF]
Revista Brasileira De Farmacognosia, 2012 Sulfated polysaccharides were extracted with acetone from brown algae Padina gymnospora. The fraction precipitated with 1.5 volumes of acetone (F1.5) purified in Sephadex G-75 was characterized by infrared and nuclear magnetic resonance of 13C and 1H, through which the presence of sulfate groups on the C4 of α-L-fucose could be observed.
Hugo Alexandre Oliveira Rocha
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A sulfated α-l-fucan from sea cucumber
Carbohydrate Research, 1994A purified sulfated alpha-L-fucan from the sea cucumber body wall was studied, before and after almost complete desulfation, using methylation analysis and NMR spectroscopy. NMR analysis indicates that 2,4-di-O-sulfo-L-fucopyranose and unsubstituted fucopyranose are present in equal proportions, and that 2-O-sulfo-L-fucopyranose is present in twice ...
A C, Ribeiro +3 more
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Inhibition of complement activation by natural sulfated polysaccharides (fucans) from brown seaweed
Molecular Immunology, 1994In the present study, we demonstrate that natural sulfated polysaccharides (fucans) isolated from brown seaweed are potent inhibitors of human complement activation. A fucan fraction of chromatographic molecular weight 22,600, termed BS8, was found to inhibit classical and alternative pathway activation in whole serum in a dose-dependent fashion. Fucan
Catherine Boisson-Vidal
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Relationship between Sulfate Groups and Biological Activities of Fucans
Thrombosis Research, 2000The anticoagulant and antiproliferative effects of low molecular weight fucans with different sulfate content were examined. The anticoagulant activity was determined by activated partial thromboplastin time and the antiproliferative one was achieved in vitro on CCL39 fibroblast cell line.
F, Haroun-Bouhedja +3 more
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Searching for Alternatives to Heparin Sulfated Fucans from Marine Invertebrates
Trends in Cardiovascular Medicine, 1999We describe a variety of sulfated polysaccharides with regular and well-defined structures which are useful tools for elucidating structure/biological function relationship. Several of these compounds have anticoagulant and antithrombotic activities.
P A, Mourão, M S, Pereira
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