Results 161 to 170 of about 1,407 (187)

Mild acid hydrolysis of sulfated fucans: a selective 2-desulfation reaction and an alternative approach for preparing tailored sulfated oligosaccharides [PDF]

Glycobiology, 2005
Sulfated fucans from marine invertebrates have simple, linear structures, composed of repeating units of oligosaccharides. Most of these polysaccharides contain 3-linked fucosyl units, but each species of invertebrate has a specific pattern of sulfation.
Vitor H Pomin, Ana Paula Valente
exaly   +3 more sources

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A highly regular fucan sulfate from the sea cucumber Stichopus horrens

Carbohydrate Research, 2018
A highly regular fucan sulfate SHFS was isolated from the sea cucumber Stichopus horrens by extraction of the body walls in the presence of papain followed by ion-exchange and gel permeation chromatography. SHFS had MW of about 140 kDa and contained fucose and sulfate in the molar ratio of about 1:1.
Nadezhda E, Ustyuzhanina, Maria I, Bilan, Andrey S, Dmitrenok, Elizaveta Yu, Borodina, Nikolay E, Nifantiev, Anatolii I, Usov   +5 more
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Conformation of sulfated galactan and sulfated fucan in aqueous solutions: Implications to their anticoagulant activities

Journal of Molecular Graphics and Modelling, 2007
The discovery of sulfated galactans and sulfated fucans in marine invertebrates with simple and ordered structures opened new perspectives to investigate the biological activity of these molecules and to determine whether different structures confer high affinity for a particular protein. We undertook a conformational analysis of a 2-sulfated, 3-linked
Camila F, Becker, Jorge A, Guimarães, Paulo A S, Mourão, Hugo, Verli   +3 more
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Five distinct fucan sulfates from sea cucumber Pattalus mollis: Purification, structural characterization and anticoagulant activities

International Journal of Biological Macromolecules, 2021
Fucan sulfates from echinoderm possess characteristic structures and various biological activities. Herein, comprehensive methods including enzymolysis, ion-exchange chromatography and size exclusion chromatography lead to the purification of five fucan sulfates (FSI, FSII, FSIII, FSIV, FSV) from the sea cucumber Pattalus mollis.
Yan, Ma, Na, Gao, Zhichuang, Zuo, Shanni, Li, Wenqi, Zheng, Xiang, Shi, Qipei, Liu, Ting, Ma, Ronghua, Yin, Xian, Li, Jinhua, Zhao   +10 more
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Antithrombin activity of a fucan sulfate from the brown seaweed Ecklonia kurome

Thrombosis Research, 1991
The mechanism of antithrombin action of a fucan sulfate (C-II), which was isolated from the brown seaweed Ecklonia kurome, was examined by clotting method using a thrombin-fibrinogen system and by amidolytic method using a chromogenic substrate in the presence and the absence of antithrombin III (AT III) or heparin cofactor II (HC II).
T, Nishino, Y, Aizu, T, Nagumo
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A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity

Carbohydrate Polymers, 2021
Marine sulfated polysaccharides have aroused widespread concern for their various structures and bioactivities. Peroxide depolymerization is a common strategy in analysis of structures and structure-activity relationships of polysaccharides. However, confirming the depolymerization process and exact structures of the degradation products is still a ...
Xiaomei, Li, Shanni, Li, Jie, Liu, Lisha, Lin, Huifang, Sun, Wenjiao, Yang, Ying, Cai, Na, Gao, Lutan, Zhou, Hongbo, Qin, Ronghua, Yin, Jinhua, Zhao   +11 more
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Structure and anticoagulant activity of a sulfated fucan from the sea cucumber Acaudina leucoprocta

International Journal of Biological Macromolecules, 2020
A sulfated fucan was extracted, purified, and characterized from Acaudina leucoprocta (a low value sea cucumber) to better understand and utilize this species. The structure of the sulfated fucan was elucidated using chemical and modern spectroscopic analyses including HPGPC, IR, AFM, GC-MS, and NMR, and its bioactivity was investigated.
Wentao, He, Haihong, Sun, Laijin, Su, Dejian, Zhou, Xing, Zhang, Deng, Shanggui, Yin, Chen   +6 more
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Mild acid hydrolysis on Fucan sulfate from Stichopus herrmanni: Structures, depolymerization mechanism and anticoagulant activity

Food Chemistry, 2022
Fucan sulfate (FS) from sea cucumbers possesses linear sequences with repeating units that differ principally in the pattern of sulfation and position of glycosidic linkage. FS from Stichopus herrmanni (ShFS) was preliminarily identified as the relatively simple structure {-3)-L-Fuc2S-(α1-}n.
Xiaomei, Li, Huifang, Sun, Zimo, Ning, Wenjiao, Yang, Ying, Cai, Ronghua, Yin, Jinhua, Zhao   +6 more
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An anticoagulant fucan sulfate with hexasaccharide repeating units from the sea cucumber Holothuria albiventer

Carbohydrate Research, 2018
A fucan sulfate was isolated and purified from the sea cucumber Holothuria albiventer by papain enzymolysis, alkaline hydrolysis and ion-exchange chromatography. The water-soluble polysaccharide had high molecular weight and contained fucose and sulfate in a molar ratio of about 1:0.83.
Ying, Cai, Wenjiao, Yang, Ronghua, Yin, Lutan, Zhou, Zhongkun, Li, Mingyi, Wu, Jinhua, Zhao   +6 more
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Role of basic amino acids in the interaction of bindin with sulfated fucans

Biochemistry, 1988
Bindin, the acrosomal sperm adhesion protein of the sea urchin Strongylocentrotus purpuratus, binds specifically and with high affinity (Kd = 10(-8) M) to egg sulfated fucans in the high ionic strength milieu of seawater (0.55 M salt). Previous studies indicated that the negatively charged sulfate groups of the polysaccharide are critical for binding ...
P L, DeAngelis, C G, Glabe
exaly   +3 more sources