Results 171 to 180 of about 1,407 (187)

Structural analysis of sulfated fucan from Saccharina japonica by electrospray ionization tandem mass spectrometry

Carbohydrate Research, 2013
Desulfation of a fucoidan from Saccharina japonica by treatment with DMSO-MeOH resulted in partial degradation of polymeric molecules by methanolysis giving rise to a mixture of neutral, monosulfated, and disulfated fucooligosaccharides in the form of methyl glycosides. These oligomeric fragments were characterized by ESI-MS and ESI-CID-MS/MS.
Weihua, Jin, Zhimou, Guo, Jing, Wang, Wenjing, Zhang, Quanbin, Zhang   +4 more
openaire   +2 more sources

In vitro and in vivo immunoregulatory activity of sulfated fucan from the sea cucumber A. leucoprocta

International Journal of Biological Macromolecules, 2021
The in vitro and in vivo immunoregulatory activity of a water-soluble sulfated fucan AL1-1 from the sea cucumber A. leucoprocta was elucidated. In vitro experiments showed that AL1-1 up-regulated immunostimulatory activities in RAW264.7 cells and that it could successfully promote ROS production and phagocytic activity, increase secretion levels of ...
Guo, Feng, Su, Laijin, Shen, Chen, Wang, Teng, Zhou, Dejian, Chen, Yin, Guo, Shoudong   +6 more
openaire   +2 more sources

Use of Sulfated Fucans as Anticoagulant and Antithrombotic Agents: Future Perspectives

Current Pharmaceutical Design, 2004
Sulfated alpha-L-fucans from brown algae (also known as fucoidan) have complex and heterogeneous structures but recent studies revealed the occurrence of ordered repeat units in the sulfated fucans from several species. Even in these cases, the presence of highly branched portions and the complex distributions of sulfate and acetyl groups highlight the
openaire   +2 more sources

Polysaccharides from the brown seaweed Padina tetrastromatica: Characterization of a sulfated fucan

Carbohydrate Polymers, 2009
Sulfated fucans, the complex polysaccharides from brown seaweeds, possess various biological activities. To understand the structure activity relationship of sulfated fucans, we have investigated the structural features of one such polymer from Padina tetrastromatica using standard methods of carbohydrate structural analysis.
Paramita Karmakar, Tuhin Ghosh, Sharmistha Sinha, Sudipta Saha, Pinaki Mandal, Pradyot K. Ghosal, Bimalendu Ray   +6 more
openaire   +1 more source

A comprehensive review of sulfated fucan from sea cucumber: Antecedent and prospect

Carbohydrate Polymers
Sulfated fucan from sea cucumber is mainly consists of L-fucose and sulfate groups. Recent studies have confirmed that the structure of sulfated fucan mainly consists of repeating units, typically tetrasaccharides. However, there is growing evidence indicating the presence of irregular domains with heterogeneous units that have not been extensively ...
Guangning, Chen, Long, Yu, Feifei, Shi, Jingjing, Shen, Yuying, Zhang, Guanchen, Liu, Xuanwei, Mei, Xinyu, Li, Xiaoqi, Xu, Changhu, Xue, Yaoguang, Chang   +10 more
openaire   +2 more sources

Structural characterization of a new anticoagulant fucan sulfate from the brown seaweed Ecklonia kurome

Carbohydrate Research, 1991
Methylation analysis of a fucose-containing, sulfated polysaccharide (C-II), which was isolated from the brown seaweed Ecklonia kurome and has a potent anticoagulant activity, showed the presence of 3-O- and 3,4-O-disubstituted fucopyranosyl residues in addition to small proportions of nonreducing, terminal fucofuranosyl and fucopyranosyl groups, and 2,
T, Nishino, T, Nagumo, H, Kiyohara, H, Yamada   +3 more
openaire   +2 more sources

NMR‐based conformation and dynamics of a tetrasaccharide‐repeating sulfated fucan substituted by different counterions

Biopolymers, 2016
AbstractThe sulfated fucan from the sea urchin Lytechinus variegatus is composed of the repetitive sequence [‐3)‐α‐l‐Fucp‐4( )‐(1‐3)‐α‐l‐Fucp‐2,4‐di( )‐(1‐3)‐α‐l‐Fucp‐2( )‐(1‐3)‐α‐l‐Fucp‐2( )‐(1‐]n. Conformation (of rings and chains) and dynamics of this tetrasaccharide‐repeating sulfated fucan substituted by Na+, Ca2+, and Li+ as counterions have been
Paulo A G, Soares, Ismael N L, Queiroz, Gustavo R C, Santos, Paulo A S, Mourão, Vitor H, Pomin   +4 more
openaire   +2 more sources

Structural investigation of Fun168A unraveling the recognition mechanism of endo-1,3-fucanase towards sulfated fucan

International Journal of Biological Macromolecules
Sulfated fucan has gained interest due to its various physiological activities. Endo-1,3-fucanases are valuable tools for investigating the structure and establishing structure-activity relationships of sulfated fucan. However, the substrate recognition mechanism of endo-1,3-fucanases towards sulfated fucan remains unclear, limiting the application of ...
Guangning, Chen, Sheng, Dong, Yuying, Zhang, Jingjing, Shen, Guanchen, Liu, Fangyi, Chen, Xinyu, Li, Changhu, Xue, Qiu, Cui, Yingang, Feng, Yaoguang, Chang   +10 more
openaire   +2 more sources

Structural characterization of a distinct fucan sulfate from Pattalus mollis through an oligosaccharide mapping approach

Carbohydrate Research
The elucidation of the precise structure of fucan sulfate is essential for understanding the structure-activity relationship and promoting potential biomedical applications. In this work, the structure of a distinct fucan sulfate fraction V (PmFS in Ref 15 and FSV in Ref 16 → PFV) from Pattalus mollis was investigated using an oligosaccharide mapping ...
Yan, Ma, Zhichuang, Zuo, Wenqi, Zheng, Ronghua, Yin, Xuewen, Wu, Yujun, Ma, Mengchen, Ji, Wenwen, Ma, Xian, Li, Weilie, Xiao, Na, Gao, Jinhua, Zhao   +11 more
openaire   +2 more sources

Systematic comparison of eight methods for preparation of high purity sulfated fucans extracted from the brown alga Pelvetia canaliculata

International Journal of Biological Macromolecules, 2022
Jasna Nikolic Chenais, Diane Jouanneau, Mathieu Fanuel   +2 more
exaly