Results 11 to 20 of about 17,770 (172)

Chemical Structures and Bioactivities of Sulfated Polysaccharides from Marine Algae

open access: yesMarine Drugs, 2011
Sulfated polysaccharides and their lower molecular weight oligosaccharide derivatives from marine macroalgae have been shown to possess a variety of biological activities.
H. Stephen Ewart   +3 more
doaj   +3 more sources

SPR Sensor-Based Analysis of the Inhibition of Marine Sulfated Glycans on Interactions between Monkeypox Virus Proteins and Glycosaminoglycans

open access: yesMarine Drugs, 2023
Sulfated glycans from marine organisms are excellent sources of naturally occurring glycosaminoglycan (GAG) mimetics that demonstrate therapeutic activities, such as antiviral/microbial infection, anticoagulant, anticancer, and anti-inflammation ...
Peng He   +10 more
doaj   +2 more sources

Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber

open access: yesMarine Drugs, 2015
Sulfated fucans, the complex polysaccharides, exhibit various biological activities. Herein, we purified two fucans from the sea cucumbers Holothuria edulis and Ludwigothurea grisea. Their structures were verified by means of HPGPC, FT-IR, GC–MS and NMR.
Mingyi Wu   +9 more
doaj   +2 more sources

Sulfated Galactofucans: An Outstanding Class of Fucoidans with Promising Bioactivities

open access: yesMarine Drugs, 2022
Fucoidans encompass versatile and heterogeneous sulfated biopolysaccharides of marine origin, specifically brown algae and marine invertebrates. Their chemistry and bioactivities have been extensively investigated in the last few decades.
Ahmed Zayed   +3 more
doaj   +2 more sources

Sulfated fucans and a sulfated galactan from sea urchins as potent inhibitors of selectin-dependent hematogenous metastasis [PDF]

open access: yesGlycobiology, 2018
Metastasis is responsible for the majority of cancer-associated deaths, though only a very small number of tumor cells are able to efficiently complete all the steps of that process. Tumor cell survival in the bloodstream is one of the limiting aspects of the metastatic cascade.
Felipe C O B Teixeira   +5 more
core   +6 more sources

Heterofucans from Dictyota menstrualis have anticoagulant activity [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 2004
Fucan is a term used to denote a family of sulfated L-fucose-rich polysaccharides which are present in the extracellular matrix of brown seaweed and in the egg jelly coat of sea urchins.
I.R.L. Albuquerque   +5 more
doaj   +2 more sources

Comparison of Physicochemical Characteristics and Anticoagulant Activities of Polysaccharides from Three Sea Cucumbers

open access: yesMarine Drugs, 2013
In order to search for sulfated polysaccharides in different invertebrate connective tissues and to examine their biological activities, we have isolated three types of polysaccharides from the body wall of the three sea cucumbers Holothuria edulis ...
Shengmin Wang   +9 more
doaj   +2 more sources

Marine medicinal glycomics [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Glycomics is an international initiative aimed to understand the structure and function of the glycans from a given type of cell, tissue, organism, kingdom or even environment, as found under certain conditions.
Vitor Hugo Pomin
doaj   +2 more sources

Brown seaweed <i>Cystoseira</i> <i>schiffneri</i> as a promising source of sulfated fucans: Seasonal variability of structural, chemical, and antioxidant properties. [PDF]

open access: yesFood Sci Nutr, 2021
International audienceThe sulfated fucans, also known as fucoidans, represented fucose-containing sulfated polysaccharides that were widely extracted from brown seaweeds.
Benslima A   +8 more
europepmc   +2 more sources

The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics

open access: yesMicroorganisms, 2017
Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
doaj   +2 more sources

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