Marine organism sulfated polysaccharides exhibiting significant antimalarial activity and inhibition of red blood cell invasion by Plasmodium [PDF]
, 2016 The antimalarial activity of heparin, against which there are no resistances known, has not been therapeutically exploited due to its potent anticoagulating activity.
Fernàndez Busquets, Xavier +3 more
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Antiproliferative activity of glycosaminoglycan-like polysaccharides derived from marine molluscs [PDF]
, 2018 Despite the increasing availability of new classes of cancer treatment, such as immuneand targeted therapies, there remains a need for the development of new antiproliferative/cytotoxic drugs with improved pharmacological profiles that can also ...
Gallagher +3 more
core +5 more sources
The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics
Microorganisms, 2017 Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
doaj +1 more source
Production of mexican brown macroalgae fucoidan and fucosidases under an integral green technology bioproceses by the biorefinery concept [PDF]
, 2015 Marine ecosystem can be considered a rather exploited source of natural substances with enormous bioactive potential. In Mexico macro-algae study remain forgotten for research and economic purposes besides the high amount of this resource along the ...
Aguilar, Cristóbal N. +6 more
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Frontiers in Cellular and Infection Microbiology, 2014 Glycomics is an international initiative aimed to understand the structure and function of the glycans from a given type of cell, tissue, organism, kingdom or even environment, as found under certain conditions.
Vitor Hugo Pomin
doaj +1 more source
In vitro anti-canine distemper virus activity of fucoidan extracted from the brown alga Cladosiphon okamuranus [PDF]
, 2014 Canine distemper virus (CDV) is a morbillivirus related to measles virus that infects dogs and other carnivores. CDV has a significant global impact on animal health; however, there is no current antiviral treatment for CDV infection. In recent years,
Cruz Suárez, Lucía Elizabeth +6 more
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Antiviral compounds obtained from microalgae commonly used as carotenoid sources [PDF]
, 2012 The final publication is available at Springer via http://dx.doi.org/10.1007/s10811-011-9692-1Pressurized liquid extraction (PLE), an environmentally friendly technique, has been used to obtain antiviral compounds from microalgae commonly used as ...
Herrero, Miguel +6 more
core +5 more sources
Marine Drugs, 2011 Fucan is a term used to denominate a family of sulfated polysaccharides rich in sulfated L-fucose. We extracted six fucans from Canistrocarpus cervicornis by proteolytic digestion followed by sequential acetone precipitation.
Hugo Alexandre Oliveira Rocha +8 more
doaj +1 more source
Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges
Marine Drugs, 2012 Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj +1 more source
Extraction of sulfated polysaccharides by autohydrolysis of brown seaweed Fucus vesiculosus [PDF]
, 2012 The extraction of sulfated polysaccharides (fucoidan) by autohydrolysis (AH) of brown seaweed Fucus vesiculosus was studied. Experimental assays were performed under different conditions of temperature (160 to 200°C) and reaction time (10 to 30 min ...
Aguilar, Cristóbal N. +4 more
core +1 more source