Results 31 to 40 of about 1,937 (151)
Molecular and functional characterization of sulfiredoxin homologs from higher plants [PDF]
Cell Research, 2006 By reducing cysteine-sulfinic acid in oxidized peroxiredoxin, sulfiredoxin (Srx) plays an important role in oxidation stress resistance in yeast and human cells. Here, we report the first molecular and functional characterization of Srx homolog from higher plants.
Xian Peng, Liu +6 more
openaire +2 more sources
Peroxiredoxin 2: An Important Element of the Antioxidant Defense of the Erythrocyte
Antioxidants, 2023 Peroxiredoxin 2 (Prdx2) is the third most abundant erythrocyte protein. It was known previously as calpromotin since its binding to the membrane stimulates the calcium-dependent potassium channel.
Izabela Sadowska-Bartosz +1 more
doaj +1 more source
Molecules, 2015 Glutaredoxin (Grx), peroxiredoxin (Prx), and thioredoxin (Trx) are redoxin family proteins that catalyze different types of chemical reactions that impact cell growth and survival through functionally distinct intracellular pathways.
Aulma R. Parker +10 more
doaj +1 more source
Piecing Together How Peroxiredoxins Maintain Genomic Stability
Antioxidants, 2018 Peroxiredoxins, a highly conserved family of thiol oxidoreductases, play a key role in oxidant detoxification by partnering with the thioredoxin system to protect against oxidative stress.
James D. West +4 more
doaj +1 more source
A novel role of the fission yeast sulfiredoxin Srx1 in heme acquisition
Molecular Microbiology, 2023 AbstractThe transporter Str3 promotes heme import in Schizosaccharomyces pombe cells that lack the heme receptor Shu1 and are deficient in heme biosynthesis. Under microaerobic conditions, the peroxiredoxin Tpx1 acts as a heme scavenger within the Str3‐dependent pathway.
Tobias Vahsen +3 more
openaire +2 more sources
Journal of Pharmaceutical Analysis, 2021 Non-small cell lung cancer (NSCLC) is often characterized by an underlying mutation in the epidermal growth factor receptor (EGFR), contributing to aggressive metastatic disease.
Ebony Nottingham +8 more
doaj +1 more source
Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages
Cells, 2019 Stefin B (cystatin B) is an intracellular inhibitor of cysteine cathepsins and mutations in the stefin B gene, resulting in the development of Unverricht−Lundborg disease, which is a form of myoclonic epilepsy. It was suggested that a key mechanism
Mojca Trstenjak Prebanda +3 more
doaj +1 more source
Cell Death and Disease, 2021 Acinar cell injury and the inflammatory response are critical bioprocesses of acute pancreatitis (AP). We investigated the role and underlying mechanism of sulfiredoxin-1 (Srxn1) in AP.
Jun He +10 more
doaj +1 more source
Mitochondrial Peroxiredoxin-IIF (PRXIIF) Activity and Function during Seed Aging
Antioxidants, 2022 Mitochondria play a major role in energy metabolism, particularly in cell respiration, cellular metabolism, and signal transduction, and are also involved in other processes, such as cell signaling, cell cycle control, cell growth, differentiation and ...
Ewelina A. Klupczyńska +3 more
doaj +1 more source
Effects of Srxn1 on growth and Notch signalling of astrocyte induced by hydrogen peroxide
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Objective To investigate the effect of Sulfiredoxin-1 (Srxn1) on astrocyte injury induced by hydrogen peroxide (H2O2).Methods Observing the changes of H2O2 on contents of lactate dehydrogenase (LDH), malondialdehyde (MDA), superoxide dismutase (SOD) and ...
Lan Li +4 more
doaj +1 more source