Results 31 to 40 of about 15,229 (210)
Journal of Cell Science, 1975 ABSTRACT The three-dimensional structure of a double-stranded DNA molecule may be described by distinguishing the helical turns of the DNA duplex from any superhelical turns that might be superimposed upon the duplex turns. There are characteristic changes in the hydrodynamic properties of superhelical DNA molecules when they interact ...
Cook, P, Brazell, I
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Biology, 2021 DNA topoisomerases are the enzymes that regulate DNA topology in all living cells. Since the discovery and purification of ω (omega), when the first were topoisomerase identified, the function of many topoisomerases has been examined.
Jorge Cebrián +5 more
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Frontiers in Microbiology, 2023 Topoisomerase IV (Topo IV) is the main decatenation enzyme in Escherichia coli; it removes catenation links that are formed during DNA replication. Topo IV binding and cleavage sites were previously identified in the E.
Dmitry Sutormin +3 more
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Stress Sensors and Signal Transducers in Cyanobacteria
Sensors, 2010 In living cells, the perception of environmental stress and the subsequent transduction of stress signals are primary events in the acclimation to changes in the environment.
Sergey Kryazhov +5 more
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Dimensions of plectonemically supercoiled DNA [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2002 With a view to determine the configuration and regularity of plectonemically supercoiled DNA, we have measured the small angle neutron scattering from pUC18 plasmid in saline solutions. Furthermore, we have derived the mathematical expression for the single chain scattering function (form factor) of a superhelical structure, including the longitudinal ...
Zakharova, Svetlana S. +5 more
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Frontiers in Microbiology, 2019 Negative DNA supercoiling allows chromosome condensation and facilitates DNA unwinding, which is required for the occurrence of DNA transaction processes, i.e., DNA replication, transcription and recombination.
Marcin Jan Szafran +4 more
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Evolution, Adaptation, and Supercoiling [PDF]
Journal of Bacteriology, 2007 Geometrical and, to some extent, physical and informational properties of covalently closed DNA molecules (or molecules that can be ideally viewed as closed) are determined by their connectivity, i.e., the number of times one strand of DNA is topologically linked to another.
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Frontiers in Cellular and Infection Microbiology, 2012 The prevalence of fluoroquinolone (FQ)-resistant Campylobacter has become a concern for public health. To facilitate the control of FQ-resistant Campylobacter, it is necessary to understand the impact of FQ resistance on the fitness of Campylobacter in ...
Jing eHan +7 more
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Nature Communications, 2022 In E. coli, disruption of TopoI and RNAP interaction decreases cells viability and leads to hypernegative DNA supercoiling and R loops accumulation. TopoI and DNA gyrase bind around transcription units and TopoI recognizes cleavage sites by a specific ...
Dmitry Sutormin +7 more
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Genome scale patterns of supercoiling in a bacterial chromosome
Nature Communications, 2016 Bacterial DNA primarily exists in a negatively supercoiled or under-wound state. Here, by mapping the supercoiling state, the authors show that there is a gradient of supercoiling across the bacterial chromosome with the terminus being more negatively ...
Avantika Lal +5 more
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