Results 41 to 50 of about 15,229 (210)
Viruses, 2018 Transposable phages, also called saltoviruses, of which the Escherichia coli phage Mu is the reference, are temperate phages that multiply their genome through replicative transposition at multiple sites in their host chromosome.
Gilles Vergnaud +5 more
doaj +1 more source
Supercoiling Theory and Model of Chromosomal Structures in Eukaryotic Cells [PDF]
, 2019 About six billion base pairs of DNA reside highly orderly in each human cell’s nucleus through their manifestation as twenty-three pairs of chromosomes.
Tianhu, Li, Hao, Zhang
core +1 more source
Mechanical Caging of Nucleic Acids Enabled by Light‐Activated Synthetic Molecular Motors
Angewandte Chemie, EarlyView.A synthetic light‐driven molecular motor imposes mechanical constraints on nucleic acids, enabling “mechanical caging” as a new mode to regulate DNA structure and function through mechanical input rather than chemical masking. ABSTRACT Control over nucleic acid activity is central to biotechnology and therapeutic development.
Yuchen Ma +10 more
wiley +2 more sources
Resonant Domain Wall Dynamics in a Three‐Dimensional Magnetic Nano Double Helix
Advanced Materials, EarlyView.3D magnetic nanostructures promise exciting possibilities for magnetization dynamics. However, experimental realizations remain scarce. In nanoprinted cobalt double helices, time‐resolved X‐ray microscopy reveals harmonic domain wall dynamics. Simulations identify the mode and additional higher‐frequency resonances, revealing a rich dynamic landscape ...
Pamela Morales‐Fernández +15 more
wiley +1 more source
The Transcriptome of Streptococcus pneumoniae Induced by Local and Global Changes in Supercoiling
Frontiers in Microbiology, 2017 The bacterial chromosome is compacted in a manner optimal for DNA transactions to occur. The degree of compaction results from the level of DNA-supercoiling and the presence of nucleoid-binding proteins.
Adela G. de la Campa +5 more
doaj +1 more source
Scientific Reports, 2021 Transcription, the first step to gene expression, is a central coordination process in all living matter. Besides a plethora of regulatory mechanisms, the promoter architecture sets the foundation of expression strength, timing and the potential for ...
Carlo A. Klein +3 more
doaj +1 more source
Molecules, 2021 Gyrase is a bacterial type IIA topoisomerase that catalyzes negative supercoiling of DNA. The enzyme is essential in bacteria and is a validated drug target in the treatment of bacterial infections.
Dagmar Klostermeier
doaj +1 more source
Functional Fibers in Soft Robotics: Advances in Material, Structural, and Systemic Tactics
Advanced Robotics Research, EarlyView.Fiber‐form robotic systems offer a scalable pathway toward embodied intelligence in soft robotics. This review surveys functional fibers as material, structural, and systemic elements, highlighting advances in responsive materials, architectural programing, and fabrication strategies.
Joonhee Won +5 more
wiley +1 more source
Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone
Advanced Science, EarlyView.A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad +12 more
wiley +1 more source
Advanced Science, EarlyView.Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao +6 more
wiley +1 more source