Results 241 to 250 of about 269,638 (309)

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

Reviewer #2 (Public review): A toolbox for ablating excitatory and inhibitory synapses

Aida Bareghamyan, Changfeng Deng, Sarah Daoudi, Scott Nawy, Xiaocen Lu, Wei Zhang, Robert E Campbell, Richard H Kramer, David M Chenoweth, Don B Arnold   +9 more
openalex   +1 more source

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

Viral modulation of synaptic pruning: implications for neuropathology and brain function. [PDF]

J Virol
Aliakbari S, Asadi S, Sayyah M, Naderi N, Salarvandian S, Khodagholi F, Gholami Pourbadie H.   +6 more
europepmc   +1 more source

Reviewer #3 (Public review): Nanophysiology Approach Reveals Diversity in Calcium Microdomains across Zebrafish Retinal Bipolar Ribbon Synapses

Nirujan Rameshkumar, Abhishek P Shrestha, Johane M Boff, Mrinalini Hoon, Victor Matveev, David Zenisek, Thirumalini Vaithianathan   +6 more
openalex   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

eLife Assessment: Single molecule counting detects low-copy glycine receptors in hippocampal and striatal synapses

Melike Lakadamyali
openalex   +1 more source

UV-Enhanced Artificial Synapses Based on WSe₂-SrAl₂O₄ Composites. [PDF]

Nanomaterials (Basel)
Sun Q, Long X, Chen C, Zhang N, Chen P.
europepmc   +1 more source

Boundary-enhanced sparse transformer for generalizable and accurate medical image segmentation. [PDF]

Sci Rep
Li C, Liu Q, Song J.
europepmc   +1 more source