Results 11 to 20 of about 471,836 (383)

Interaction and Subcellular Association of PRRT1/SynDIG4 With AMPA Receptors

open access: yesFrontiers in Synaptic Neuroscience, 2021
AMPA receptors (AMPAR) are organized into supramolecular complexes in association with other membrane proteins that provide exquisite regulation of their biophysical properties and subcellular trafficking.
Emily Eischen Martin   +3 more
doaj   +1 more source

The implication of a diversity of non-neuronal cells in disorders affecting brain networks

open access: yesFrontiers in Cellular Neuroscience, 2022
In the central nervous system (CNS) neurons are classically considered the functional unit of the brain. Analysis of the physical connections and co-activation of neurons, referred to as structural and functional connectivity, respectively, is a metric ...
Micaël Carrier   +11 more
doaj   +1 more source

Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulated in Exercise in a Mouse Model of Parkinson’s Disease

open access: yesFrontiers in Aging Neuroscience, 2022
BackgroundExercise plays an essential role in improving motor symptoms in Parkinson’s disease (PD), but the underlying mechanism in the central nervous system remains unclear.MethodsMotor ability was observed after 12-week treadmill exercise on a 1 ...
Weifang Tong   +12 more
doaj   +1 more source

Large-Scale and Flexible Optical Synapses for Neuromorphic Computing and Integrated Visible Information Sensing Memory Processing.

open access: yesACS Nano, 2020
Optoelectronic synapses integrating synaptic and optical-sensing functions exhibit large advantages in neuromorphic computing for visual information processing and complex learning, recognition, and memory in an energy-efficient way.
Ya-Xin Hou   +10 more
semanticscholar   +1 more source

Neuromorphic computing with multi-memristive synapses [PDF]

open access: yesNature Communications, 2017
Neuromorphic computing has emerged as a promising avenue towards building the next generation of intelligent computing systems. It has been proposed that memristive devices, which exhibit history-dependent conductivity modulation, could efficiently ...
I. Boybat   +9 more
semanticscholar   +1 more source

Neurofilament Levels in Dendritic Spines Associate with Synaptic Status

open access: yesCells, 2023
Neurofilaments are one of the main cytoskeletal components in neurons; they can be found in the form of oligomers at pre- and postsynapses. How their presence is regulated at the postsynapse remains largely unclear.
Clara-Marie Gürth   +5 more
doaj   +1 more source

Clusters of synaptic inputs on dendrites of layer 5 pyramidal cells in mouse visual cortex

open access: yeseLife, 2016
The spatial organization of synaptic inputs on the dendritic tree of cortical neurons plays a major role for dendritic integration and neural computations, yet, remarkably little is known about it.
Onur Gökçe   +2 more
doaj   +1 more source

Modeling Maintenance of Long-Term Potentiation in Clustered Synapses, Long-Term Memory Without Bistability [PDF]

open access: yes, 2015
Memories are stored, at least partly, as patterns of strong synapses. Given molecular turnover, how can synapses maintain strong for the years that memories can persist?
Smolen, Paul
core   +4 more sources

The Dynamic Synapse [PDF]

open access: yesNeuron, 2013
The constant dynamic movement of synapses and their components has emerged in the last decades as a key feature of synaptic transmission and its plasticity. Intramolecular protein movements drive conformation changes important to transduce transmitter binding into signaling. Constant cytoskeletal rearrangements power synapse shape movements.
Daniel Choquet, Antoine Triller
openaire   +2 more sources

Aberrant Synaptic Pruning in CNS Diseases: A Critical Player in HIV-Associated Neurological Dysfunction?

open access: yesCells, 2022
Even in the era of effective antiretroviral therapies, people living with Human Immunodeficiency Virus (HIV) are burdened with debilitating neurological dysfunction, such as HIV-associated neurocognitive disorders (HAND) and HIV-associated pain, for ...
Zachary Watson, Shao-Jun Tang
doaj   +1 more source

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