Results 21 to 30 of about 466,973 (293)

Decoding Synapses [PDF]

open access: yesThe Journal of Neuroscience, 1996
The strength of many synapses is modified by various use and time-dependent processes, including facilitation and depression. A general description of synaptic transfer characteristics must account for the history-dependence of synaptic efficacy and should be able to predict the postsynaptic response to any temporal pattern of presynaptic activity.
K, Sen   +3 more
openaire   +2 more sources

Aberrant Synaptic Pruning in CNS Diseases: A Critical Player in HIV-Associated Neurological Dysfunction?

open access: yesCells, 2022
Even in the era of effective antiretroviral therapies, people living with Human Immunodeficiency Virus (HIV) are burdened with debilitating neurological dysfunction, such as HIV-associated neurocognitive disorders (HAND) and HIV-associated pain, for ...
Zachary Watson, Shao-Jun Tang
doaj   +1 more source

Rapid, learning-induced inhibitory synaptogenesis in murine barrel field [PDF]

open access: yes, 2010
The structure of neurons changes during development and in response to injury or alteration in sensory experience. Changes occur in the number, shape, and dimensions of dendritic spines together with their synapses. However, precise data on these changes
Cybulska-Klosowicz, A   +6 more
core   +1 more source

A CMOS Spiking Neuron for Brain-Inspired Neural Networks with Resistive Synapses and In-Situ Learning [PDF]

open access: yes, 2015
Nanoscale resistive memories are expected to fuel dense integration of electronic synapses for large-scale neuromorphic system. To realize such a brain-inspired computing chip, a compact CMOS spiking neuron that performs in-situ learning and computing ...
Balagopal, Sakkarapani   +3 more
core   +3 more sources

Electrochemistry at the Synapse [PDF]

open access: yesAnnual Review of Analytical Chemistry, 2019
Electrochemical measurements of neurotransmitters provide insight into the dynamics of neurotransmission. In this review, we describe the development of electrochemical measurements of neurotransmitters and how they started with extrasynaptic measurements but now are pushing toward synaptic measurements.
Mimi, Shin   +3 more
openaire   +2 more sources

Connexin36 Expression in the Mammalian Retina: A Multiple-Species Comparison

open access: yesFrontiers in Cellular Neuroscience, 2017
Much knowledge about interconnection of human retinal neurons is inferred from results on animal models. Likewise, there is a lack of information on human retinal electrical synapses/gap junctions (GJ).
Tamás Kovács-Öller   +25 more
doaj   +1 more source

A Review of Graphene‐Based Memristive Neuromorphic Devices and Circuits

open access: yesAdvanced Intelligent Systems, 2023
As data processing volume increases, the limitations of traditional computers and the need for more efficient computing methods become evident. Neuromorphic computing mimics the brain's low‐power and high‐speed computations, making it crucial in the era ...
Ben Walters   +3 more
doaj   +1 more source

Structural basis of astrocytic Ca2+ signals at tripartite synapses

open access: yesNature Communications, 2020
Astrocytic Ca2+ signals can be fast and local, supporting the idea that astrocytes have the ability to regulate single synapses. However, the anatomical basis of such specific signaling remains unclear, owing to difficulties in resolving the spongiform ...
Misa Arizono   +13 more
semanticscholar   +1 more source

Spatial representation of temporal information through spike timing dependent plasticity [PDF]

open access: yes, 2003
We suggest a mechanism based on spike time dependent plasticity (STDP) of synapses to store, retrieve and predict temporal sequences. The mechanism is demonstrated in a model system of simplified integrate-and-fire type neurons densely connected by STDP ...
A. Herz   +45 more
core   +3 more sources

State based model of long-term potentiation and synaptic tagging and capture [PDF]

open access: yes, 2009
Recent data indicate that plasticity protocols have not only synapse-specific but also more widespread effects. In particular, in synaptic tagging and capture (STC), tagged synapses can capture plasticity-related proteins, synthesized in response to ...
A Govindarajan   +50 more
core   +10 more sources

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