Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]
, 2013 During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Dunwiddie TV +3 more
core +1 more source
A CMOS Spiking Neuron for Brain-Inspired Neural Networks with Resistive Synapses and In-Situ Learning [PDF]
, 2015 Nanoscale resistive memories are expected to fuel dense integration of electronic synapses for large-scale neuromorphic system. To realize such a brain-inspired computing chip, a compact CMOS spiking neuron that performs in-situ learning and computing ...
Balagopal, Sakkarapani +3 more
core +3 more sources
Rapid, learning-induced inhibitory synaptogenesis in murine barrel field [PDF]
, 2010 The structure of neurons changes during development and in response to injury or alteration in sensory experience. Changes occur in the number, shape, and dimensions of dendritic spines together with their synapses. However, precise data on these changes
Cybulska-Klosowicz, A +6 more
core +1 more source
Synapses immunologiques et synapses neuronales [PDF]
médecine/sciences, 2003 Les systemes nerveux et immunitaire ont en commun de constituer dans l’organisme des reseaux complexes de cellules en interaction. Dans ces reseaux transitent en permanence d’enormes quantites d’informations, codees de facon tres differente dans les deux cas. Ces informations doivent en particulier circuler de cellule en cellule.
Trautmann, Alain +3 more
openaire +2 more sources
Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
Nature Communications, 2017 Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during neuronal circuit formation. Disruption of signaling between microglia and neurons leads to an excess of immature synaptic connections, thought to be the result ...
L. Weinhard +11 more
semanticscholar +1 more source
Connexin36 Expression in the Mammalian Retina: A Multiple-Species Comparison
Frontiers in Cellular Neuroscience, 2017 Much knowledge about interconnection of human retinal neurons is inferred from results on animal models. Likewise, there is a lack of information on human retinal electrical synapses/gap junctions (GJ).
Tamás Kovács-Öller +25 more
doaj +1 more source
A Review of Graphene‐Based Memristive Neuromorphic Devices and Circuits
Advanced Intelligent Systems, 2023 As data processing volume increases, the limitations of traditional computers and the need for more efficient computing methods become evident. Neuromorphic computing mimics the brain's low‐power and high‐speed computations, making it crucial in the era ...
Ben Walters +3 more
doaj +1 more source
Optimal learning rules for discrete synapses [PDF]
, 2008 There is evidence that biological synapses have a limited number of discrete weight states. Memory storage with such synapses behaves quite differently from synapses with unbounded, continuous weights, as old memories are automatically overwritten by new
Barrett, Adam B, van Rossum, M C W
core +10 more sources
Spatial representation of temporal information through spike timing dependent plasticity [PDF]
, 2003 We suggest a mechanism based on spike time dependent plasticity (STDP) of synapses to store, retrieve and predict temporal sequences. The mechanism is demonstrated in a model system of simplified integrate-and-fire type neurons densely connected by STDP ...
A. Herz +45 more
core +3 more sources
Structural basis of astrocytic Ca2+ signals at tripartite synapses
Nature Communications, 2020 Astrocytic Ca2+ signals can be fast and local, supporting the idea that astrocytes have the ability to regulate single synapses. However, the anatomical basis of such specific signaling remains unclear, owing to difficulties in resolving the spongiform ...
Misa Arizono +13 more
semanticscholar +1 more source