Results 21 to 30 of about 445,271 (401)

The implication of a diversity of non-neuronal cells in disorders affecting brain networks

open access: yesFrontiers in Cellular Neuroscience, 2022
In the central nervous system (CNS) neurons are classically considered the functional unit of the brain. Analysis of the physical connections and co-activation of neurons, referred to as structural and functional connectivity, respectively, is a metric ...
Micaël Carrier   +11 more
doaj   +1 more source

Rostral and caudal basolateral amygdala engage distinct circuits in the prelimbic and infralimbic prefrontal cortex

open access: yeseLife, 2022
Connections from the basolateral amygdala (BLA) to medial prefrontal cortex (PFC) regulate memory and emotion and become disrupted in neuropsychiatric disorders.
Kasra Manoocheri, Adam G Carter
doaj   +1 more source

Heterosynaptic Plasticity and the Experience-Dependent Refinement of Developing Neuronal Circuits

open access: yesFrontiers in Neural Circuits, 2021
Neurons remodel the structure and strength of their synapses during critical periods of development in order to optimize both perception and cognition.
Kyle R. Jenks   +4 more
doaj   +1 more source

Cell-type specific innervation of cortical pyramidal cells at their apical dendrites

open access: yeseLife, 2020
We investigated the synaptic innervation of apical dendrites of cortical pyramidal cells in a region between layers (L) 1 and 2 using 3-D electron microscopy applied to four cortical regions in mouse.
Ali Karimi   +4 more
doaj   +1 more source

Exact mean-field theory explains the dual role of electrical synapses in collective synchronization [PDF]

open access: yesPhys. Rev. Lett. 125, 248101 (2020), 2020
Electrical synapses play a major role in setting up neuronal synchronization, but the precise mechanisms whereby these synapses contribute to synchrony are subtle and remain elusive. To investigate these mechanisms mean-field theories for quadratic integrate-and-fire neurons with electrical synapses have been recently put forward.
arxiv   +1 more source

Neuromorphic computing with multi-memristive synapses [PDF]

open access: yesNature Communications, 2017
Neuromorphic computing has emerged as a promising avenue towards building the next generation of intelligent computing systems. It has been proposed that memristive devices, which exhibit history-dependent conductivity modulation, could efficiently ...
I. Boybat   +9 more
semanticscholar   +1 more source

Large-Scale and Flexible Optical Synapses for Neuromorphic Computing and Integrated Visible Information Sensing Memory Processing.

open access: yesACS Nano, 2020
Optoelectronic synapses integrating synaptic and optical-sensing functions exhibit large advantages in neuromorphic computing for visual information processing and complex learning, recognition, and memory in an energy-efficient way.
Ya-Xin Hou   +10 more
semanticscholar   +1 more source

Clusters of synaptic inputs on dendrites of layer 5 pyramidal cells in mouse visual cortex

open access: yeseLife, 2016
The spatial organization of synaptic inputs on the dendritic tree of cortical neurons plays a major role for dendritic integration and neural computations, yet, remarkably little is known about it.
Onur Gökçe   +2 more
doaj   +1 more source

Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulated in Exercise in a Mouse Model of Parkinson’s Disease

open access: yesFrontiers in Aging Neuroscience, 2022
BackgroundExercise plays an essential role in improving motor symptoms in Parkinson’s disease (PD), but the underlying mechanism in the central nervous system remains unclear.MethodsMotor ability was observed after 12-week treadmill exercise on a 1 ...
Weifang Tong   +12 more
doaj   +1 more source

Systemic Inflammation Accelerates Changes in Microglial and Synaptic Markers in an Experimental Model of Chronic Neurodegeneration

open access: yesFrontiers in Neuroscience, 2022
Bacterial infections are a common cause of morbidity and mortality in the elderly, and particularly in individuals with a neurodegenerative disease. Experimental models of neurodegeneration have shown that LPS-induced systemic inflammation increases ...
Joe K. Chouhan   +3 more
doaj   +1 more source

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