Results 31 to 40 of about 530,363 (319)
eLife, 2019 Synapses and circuits rely on neuroplasticity to adjust output and meet physiological needs. Forms of homeostatic synaptic plasticity impart stability at synapses by countering destabilizing perturbations. The Drosophila melanogaster larval neuromuscular
Thomas D James +2 more
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Synaptic structure and diffusion dynamics of synaptic receptors [PDF]
Biology of the Cell, 2003 AbstractNeurotransmitter receptors are concentrated at synaptic sites through interactions with specific scaffolding proteins and cytoskeletal elements, but can also be found in intracellular compartments or dispersed in the membrane. The notion has emerged in recent years that this distribution results from a dynamic equilibrium between the different ...
Antoine, Triller, Daniel, Choquet
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Frontiers in Neuroscience, 2014 Cranial visceral afferents contained within the solitary tract (ST) contact second-order neurons in the nucleus of the solitary tract (NTS) and release the excitatory amino acid glutamate via three distinct exocytosis pathways; synchronous, asynchronous,
Axel J. Fenwick +2 more
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Neuroprotective astroglial response to neural damage and its relevance to affective disorders
Exploration of Neuroprotective Therapy, 2023 Astrocytes not only support neuronal function with essential roles in synaptic neurotransmission, action potential propagation, metabolic support, or neuroplastic and developmental adaptations.
José Javier Miguel-Hidalgo
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Morphologic and functional correlates of synaptic pathology in the cathepsin D knockout mouse model of congenital neuronal ceroid lipofuscinosis [PDF]
, 2011 Mutations in the cathepsin D (CTSD) gene cause an aggressive neurodegenerative disease (congenital neuronal ceroid lipofuscinosis) that leads to early death. Recent evidence suggests that presynaptic abnormalities play a major role in the pathogenesis of
Koch, Sabine +15 more
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Clinical and Translational Discovery, 2022 The rapid growth of the number of surgical cases in the world has brought opportunities and challenges to the development of anaesthesia. Modern anaesthesia technology provides safe and effective anaesthesia for hundreds of millions of surgical ...
Ningning Li +4 more
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A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]
, 2008 Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Fox Michael A +12 more
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Functional adaptation of cortical interneurons to attenuated activity is subtype-specific
Frontiers in Neural Circuits, 2012 Functional neuronal homeostasis has been studied in a variety of model systems and contexts. Many studies have shown that there are a number of changes that can be activated within individual cells or networks in order to compensate for perturbations or ...
Theofanis eKarayannis +2 more
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Synaptic Transmission: Kinetics of synaptic-vesicle recycling [PDF]
Current Biology, 1995 The kinetics of different steps in synaptic-vesicle recycling, including exocytosis, internalization and repriming, have recently been estimated in various types of living cell.
Betz, William J., Wu, Ling-Gang
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SALM/Lrfn Family Synaptic Adhesion Molecules
Frontiers in Molecular Neuroscience, 2018 Synaptic adhesion-like molecules (SALMs) are a family of cell adhesion molecules involved in regulating neuronal and synapse development that have also been implicated in diverse brain dysfunctions, including autism spectrum disorders (ASDs). SALMs, also
Eunkyung Lie +4 more
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