Results 31 to 40 of about 304,453 (323)
Tadr is an axonal histidine transporter required for visual neurotransmission in Drosophila
eLife, 2022 Neurotransmitters are generated by de novo synthesis and are essential for sustained, high-frequency synaptic transmission. Histamine, a monoamine neurotransmitter, is synthesized through decarboxylation of histidine by histidine decarboxylase (Hdc ...
Yongchao Han, Lei Peng, Tao Wang
doaj +1 more source
IBRO Reports, 2019 Amyloid β protein (Aβ) is closely related to the progression of Alzheimer's disease because senile plaques consisting of Aβ cause synaptic depression and synaptic abnormalities.
Kohei Oyabu +5 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2021 Riluzole (2-amino-6-(trifluoromethoxy)benzothiazole) is a drug known for its inhibitory effect on glutamatergic transmission and its anti-nociceptive and anti-allodynic effects in neuropathic pain rat models.
Ryo Taiji +6 more
doaj +1 more source
mGluR-dependent synaptic plasticity in drug-seeking.
Frontiers in Pharmacology, 2012 A primary feature of drug addiction is the compulsive use despite negative consequences. A general consensus is emerging on the capacity of addictive substances to co-opt synaptic transmission and synaptic plasticity in brain circuits which are involved ...
Camilla eBellone +3 more
doaj +1 more source
Differential localization of glutamate receptor subunits at the drosophila neuromuscular junction [PDF]
, 2004 The subunit composition of postsynaptic neurotransmitter receptors is a key determinant of synaptic physiology. Two glutamate receptor subunits, Drosophila glutamate receptor IIA (DGluRIIA) and DGluRIIB, are expressed at the Drosophila neuromuscular ...
Allen, Marcus James +4 more
core +1 more source
Interactions between short-term and long-term plasticity: shooting for a moving target [PDF]
, 2011 Far from being static transmission units, synapses are highly dynamical elements that change over multiple time scales depending on the history of the neural activity of both the pre- and postsynaptic neuron.
Jean-Pascal Pfister, Má
core +2 more sources
Synaptic Noise Facilitates the Emergence of Self-Organized Criticality in the Caenorhabditis elegans Neuronal Network [PDF]
, 2017 Avalanches with power-law distributed size parameters have been observed in neuronal networks. This observation might be a manifestation of the self-organized criticality (SOC).
Çiftçi, Koray
core +2 more sources
eLife, 2017 Synaptic vesicle release properties vary between neuronal cell types, but in most cases the molecular basis of this heterogeneity is unknown. Here, we compare in vivo synaptic properties of two neuronal classes in the C.
Donovan Ventimiglia, Cornelia I Bargmann
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Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming
eLife, 2022 Synapses contain a limited number of synaptic vesicles (SVs) that are released in response to action potentials (APs). Therefore, sustaining synaptic transmission over a wide range of AP firing rates and timescales depends on SV release and replenishment.
Christian Keine +9 more
doaj +1 more source
NPY-mediated synaptic plasticity in the extended amygdala prioritizes feeding during starvation
Nature CommunicationsEfficient control of feeding behavior requires the coordinated adjustment of complex motivational and affective neurocircuits. Neuropeptides from energy-sensing hypothalamic neurons are potent feeding modulators, but how these endogenous signals shape ...
Stephan Dodt +7 more
doaj +1 more source